Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12953405 | 0.77 | CDK2 (0.40) | — | |
| SCHEMBL13304699 | 0.69 | KDM4E (0.31) | — | |
| SCHEMBL13146264 | 0.62 | CDK2 (0.37) | — | |
| SCHEMBL12952968 | 0.59 | CDK9 (0.37) | PDE10A | |
| SCHEMBL21573355 | 0.59 | TAS1R3 (0.36) | — | |
| SCHEMBL12953240 | 0.57 | GSK3B (0.55) | — | |
| SCHEMBL14560679 | 0.56 | ADORA1 (0.36) | — | |
| SCHEMBL21078310 | 0.56 | PSMB5 (0.36) | — | |
| SCHEMBL8130407 | 0.56 | MDM2 (0.45) | — | |
| SCHEMBL13983010 | 0.56 | SLC6A3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7161003-B1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |
| US-7161003-B1 | Pyrazolopyrimidines as cyclin dependent kinase inhibitors | SCHERING CORPORATION (US) | 2007-01-09 | — | — | US | disclosed |