Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450615 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A | |
| SCHEMBL29648886 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A | |
| SCHEMBL29450632 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A | |
| SCHEMBL714591 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A | |
| SCHEMBL547207 | 1.00 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A | |
| SCHEMBL7532913 | 0.92 | MIF (0.45) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A | |
| SCHEMBL7532922 | 0.92 | MIF (0.45) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A | |
| SCHEMBL331134 | 0.82 | MIF (0.39) | ALDH1A1CYP1A2LMNA | |
| SCHEMBL8850662 | 0.82 | AKR1B1 (0.35) | ADRA2AADRA2BADRA2CADRA1AADRA1D | |
| SCHEMBL3886974 | 0.82 | MIF (0.52) | ALDH1A1CYP1A2CYP2C9CYP2C19ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 232 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-4463176-A | REGENERATION OF SEPARATED CHIRAL ISOCYANATE-TREATED ADRENERGIC BLOCKING AGENTS USING HYDRAZINE HYDRATE AND A KETO ACID | MEAD JOHNSON & COMPANY (US) | 1984-07-31 | — | — | US | claimed |
| JP-9297126-A | — | — | None | — | — | JP | disclosed |
| US-11760750-B1 | Process for preparing levoketoconazole | NURAY CHEMICALS PRIVATE LIMITED (IN) | 2023-09-19 | — | — | US | disclosed |
| US-11452712-B2 | Methods and compositions involving (S)-bucindolol | ARCA BIOPHARMA INC. (US) | 2022-09-27 | — | — | US | disclosed |
| CN-111944515-B | Circular polarization luminescent material and preparation method and application thereof | 中国科学院化学研究所 | 2022-05-10 | — | — | CN | disclosed |
| US-11215583-B2 | Methods for detection of sample enantiomers using differential mobility spectrometry | DH TECHNOLOGIES DEVELOPMENT PTE. LTD. (SG) | 2022-01-04 | — | — | US | disclosed |
| US-20210228508-A1 | COMPOSITIONS AND METHODS THEREOF | Exciva GmbH | 2021-07-29 | — | — | US | disclosed |
| CN-111944515-A | Circular polarization luminescent material and preparation method and application thereof | 中国科学院化学研究所 | 2020-11-17 | — | — | CN | disclosed |
| CN-110455960-A | The method for detecting enantiomter content in (S)-(-) -3- amino quinine cyclammonium dihydrochloride | SHANDONG QIDU PHARMACEUTICAL | 2019-11-15 | — | — | CN | disclosed |
| EP-0105745-A2 | Packing materials for chromatographic use and their employment in analysing enantiomeric mixtures | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-04-18 | — | — | EP | disclosed |
| EP-0038617-B1 | DIASTEREOMERS OF AMINO ACID ESTERS, PESTICIDAL COMPOSITIONS INCLUDING THEM AND METHOD OF CONTROLLING PESTS USING THEM | ZOECON CORPORATION (US) | 1983-07-20 | — | — | EP | disclosed |
| US-4380653-A | HYPOTENSIVES, CARDIOVASCULAR DISORDERS | CIBA-GEIGY CORPORATION (US) | 1983-04-19 | — | — | US | disclosed |
| EP-0050585-A1 | 1,5-Bis-(1,4-benzodioxin-2-yl)-3-azapentane-1,5 diols, process for their preparation, pharmaceutical preparations containing them and their therapeutical use | CIBA-GEIGY AG (CH) | 1982-04-28 | — | — | EP | disclosed |
| US-4313955-A | HYPOTESIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-02-02 | — | — | US | disclosed |
| EP-0038617-A1 | Diastereomers of amino acid esters, pesticidal compositions including them and method of controlling pests using them | ZOECON CORPORATION (US) | 1981-10-28 | — | — | EP | disclosed |
| US-4276230-A | Cyano-3-phenoxybenzyl N-1-(1-naphthyl) ethylcarbamate | ZOECON CORPORATION (US) | 1981-06-30 | — | — | US | disclosed |
| US-4260633-A | INSECTICIDES, MITICIDES | ZOECON CORPORATION (US) | 1981-04-07 | — | — | US | disclosed |
| US-4259348-A | DIASTEREOMERS, INSECTICIDES, MITICIDES | ZOECON CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210228508-A1 | COMPOSITIONS AND METHODS THEREOF | CYP21A2, CYP2C19, CYP2F1 | ALDH1A1 289/4885CYP1A2 15/4885CYP2C9 4/4885 |
| US-11452712-B2 | Methods and compositions involving (S)-bucindolol | ADRB3, ADRB2, ADRB1 | ALDH1A1 1011/4885CYP1A2 116/4885CYP2C9 52/4885 |
| US-11760750-B1 | Process for preparing levoketoconazole | KHK, KYAT3, PLK3 | ALDH1A1 2659/4885CYP1A2 209/4885CYP2C9 108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.