Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29750183 | 1.00 | GLS (0.61) | GLSCASP3RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL31622484 | 0.87 | MAPT (0.62) | GLSRAB9ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL5312972 | 0.87 | MAPT (0.62) | GLSRAB9ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL22595590 | 0.86 | GLS (0.47) | GLSCASP3RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11608773 | 0.86 | GLS (0.47) | GLSCASP3RAB9ASMN1; SMN2NPC1 | |
| Ethane SCHEMBL11477216 | 0.86 | ALDH1A1 (0.49) | GLSMAPTALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6699936 | 0.85 | GLS (0.71) | GLSCASP3RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL2884712 | 0.85 | TDP1 (0.61) | GLSRAB9ASMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL6786134 | 0.84 | TDP1 (0.64) | RAB9ASMN1; SMN2TDP1L3MBTL1MAPT | |
| SCHEMBL9536378 | 0.84 | TDP1 (0.64) | RAB9ASMN1; SMN2TDP1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113896809-A | Modified sodium alginate, preparation method thereof, pressure-sensitive adhesive and patch | 安徽徽科生物工程技术有限公司 | 2022-01-07 | — | — | CN | claimed |
| US-6187083-B1 | INK COMPOSITION COMPRISING SELECTED INK VEHICLE, AMIDE VISCOSITY MODIFIER, CONDUCTIVE SULFONATE SALT ALL HAVING MELTING POINTS WITHIN SPECIFIED RANGE, COLORANT, OPTIONAL ANTIOXIDANT AND ULTRAVIOLET ABSORBER | XEROX CORPORATION | 2001-02-13 | — | — | US | claimed |
| US-12551580-B2 | Heterocyclic compounds and imaging agents for imaging Huntington protein | CHDI FOUNDATION, INC. (US) | 2026-02-17 | — | — | US | disclosed |
| US-20240342317-A1 | HETEROCYCLIC COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | CHDI FOUNDATION, INC. | 2024-10-17 | — | — | US | disclosed |
| US-11918662-B2 | Heterocyclic compounds and imaging agents for imaging huntingtin protein | CHDI FOUNDATION, INC. (US) | 2024-03-05 | — | — | US | disclosed |
| CN-114437028-B | Method for generating N-substituted phthalimide compound by nickel-catalyzed carbonylation reaction | 桂林理工大学 | 2023-11-17 | — | — | CN | disclosed |
| CN-116075512-A | Heterocyclic compounds and imaging agents for imaging huntingtin | CHDI基金会股份有限公司 | 2023-05-05 | — | — | CN | disclosed |
| EP-4165044-A1 | HETEROCYCLIC COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | CHDI Foundation, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |
| CN-114437028-A | Method for generating N-substituted phthalimide compound through nickel-catalyzed carbonylation reaction | 桂林理工大学 | 2022-05-06 | — | — | CN | disclosed |
| CN-113896809-A | Modified sodium alginate, preparation method thereof, pressure-sensitive adhesive and patch | 安徽徽科生物工程技术有限公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-113896809-A | Modified sodium alginate, preparation method thereof, pressure-sensitive adhesive and patch | 安徽徽科生物工程技术有限公司 | 2022-01-07 | — | — | CN | disclosed |
| EP-0108854-B1 | DRUG FOR STIMULATING HEPATIC CELL HOMEOSTASIS AND FOR RESTORING THE FUNCTIONAL CAPACITY OF THE HEPATOCYTES | ARCONTHORN LIMITED (GB) | 1986-04-23 | — | — | EP | disclosed |
| US-4511580-A | AMINOETHYLTHIOSULFONIC ACID | ARCONTHORN LIMITED (GB) | 1985-04-16 | — | — | US | disclosed |
| US-4508733-A | AMINOETHANETHIOSULFONIC ACID | ARCONTHORN LIMITED (GB) | 1985-04-02 | — | — | US | disclosed |
| EP-0108854-A1 | Drug for stimulating hepatic cell homeostasis and for restoring the functional capacity of the hepatocytes | ARCONTHORN LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |
| US-4283338-A | MAINTAINING LIBERATED HYDROGEN CHLORIDE IN REACTION SYSTEM | BOOTS HERCULES AGROCHEMICALS CO. (US) | 1981-08-11 | — | — | US | disclosed |
| US-4283335-A | Process for producing dialkyl dithiophosphoric acid esters | BOOTS HERCULES AGROCHEMICALS CO. (US) | 1981-08-11 | — | — | US | disclosed |
| US-4229456-A | SUPPRESSION OF GASTRIC SECRETIONS | MERCK & CO., INC. (US) | 1980-10-21 | — | — | US | disclosed |
| EP-0000490-A1 | Substituted naphthyridinones, processes for their preparations and therapeutical applications | MERCK & CO. INC. (US) | 1979-02-07 | — | — | EP | disclosed |
| US-4133885-A | GASTRIC SECRETIONS INHIBITORS | MERCK & CO., INC. (US) | 1979-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11918662-B2 | Heterocyclic compounds and imaging agents for imaging huntingtin protein | HTT, HYPK, HSPBP1 | GLS 2116/4885CASP3 2961/4885RAB9A 1217/4885 |
| US-12551580-B2 | Heterocyclic compounds and imaging agents for imaging Huntington protein | HTT, HYPK, HIRA | GLS 1483/4885CASP3 3417/4885RAB9A 1023/4885 |
| US-20240342317-A1 | HETEROCYCLIC COMPOUNDS AND IMAGING AGENTS FOR IMAGING HUNTINGTIN PROTEIN | HTT, HYPK, HSPBP1 | GLS 2116/4885CASP3 2961/4885RAB9A 1217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.