Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C8 | P10632 | 1/20 | 0.58 |
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | FPR2 | P25090 | 2/20 | 0.49 |
| ▸ | HNF4A | P41235 | 1/20 | 0.49 |
| ▸ | KLRK1 | P26718 | 2/20 | 0.47 |
| ▸ | MICA | Q29983 | 2/20 | 0.47 |
| ▸ | RAET1L | Q5VY80 | 2/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xenalipin SCHEMBL29881739 | 1.00 | CYP2C8 (0.58) | CYP2C8KIF11GAABACE1TACR1 | |
| Xenalipin SCHEMBL3723586 | 0.98 | CYP2C8 (0.56) | CYP2C8KIF11GAABACE1TACR1 | |
| Xenalipin SCHEMBL27618270 | 0.91 | CYP2C8 (0.65) | CYP2C8KIF11GAABACE1TACR1 | |
| SCHEMBL29979035 | 0.86 | TACR1 (0.48) | CYP2C8TACR1HNF4ABCAT2LTB4R2 | |
| SCHEMBL23353984 | 0.86 | TACR1 (0.48) | CYP2C8TACR1HNF4ABCAT2LTB4R2 | |
| SCHEMBL18759613 | 0.84 | HNF4A (0.63) | HNF4ABCAT2LTB4R2 | |
| SCHEMBL30292805 | 0.84 | HNF4A (0.63) | HNF4ABCAT2LTB4R2 | |
| SCHEMBL403609 | 0.84 | GAA (0.51) | CYP2C8KIF11GAABACE1TACR1 | |
| SCHEMBL2564888 | 0.84 | BCAT2 (0.65) | CYP2C8KIF11GAABACE1TACR1 | |
| SCHEMBL171542 | 0.84 | TRPV1 (0.54) | CYP2C8KIF11GAABACE1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 795 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | claimed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | claimed |
| US-10934251-B2 | Process for the preparation of lomitapide | HETERO RESEARCH FOUNDATION (IN) | 2021-03-02 | — | — | US | claimed |
| US-20200190018-A1 | Process For The Preparation of Lomitapide | HETERO RESEARCH FOUNDATION (IN) | 2020-06-18 | — | — | US | claimed |
| US-20180291773-A1 | PROCESS FOR THE PREPARATION OF LOMITAPIDE | HETERO RESEARCH FOUNDATION (IN) | 2018-10-11 | — | — | US | claimed |
| US-20180282257-A1 | Aromatic Monoester Compositions and Processes for Preparing Same | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-10-04 | — | — | US | claimed |
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| US-20180105487-A1 | PROCESS FOR THE PREPARATION OF LOMITAPIDE | HETERO RESEARCH FOUNDATION (IN) | 2018-04-19 | — | — | US | claimed |
| EP-3215490-A1 | PROCESS FOR THE PREPARATION OF LOMITAPIDE | Hetero Research Foundation (IN) | 2017-09-13 | — | — | EP | claimed |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | claimed |
| WO-1998023593-A1 | APO B-SECRETION/MTP INHIBITORY AMIDES | PFIZER INC. (US) | 1998-06-04 | — | — | WO | claimed |
| EP-0832069-A1 | BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION | PFIZER INC. (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1997027331-A9 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | — | 1997-10-09 | — | — | WO | claimed |
| WO-1997027331-A2 | METHODS AND COMPOSITIONS FOR DETERMINING THE SEQUENCE OF NUCLEIC ACID MOLECULES | RAPIGENE, INC. (US) | 1997-07-31 | — | — | WO | claimed |
| WO-1997027327-A2 | METHODS AND COMPOSITIONS FOR DETECTING BINDING OF LIGAND PAIR USING NON-FLUORESCENT LABEL | RAPIGENE, INC. (US) | 1997-07-31 | — | — | WO | claimed |
| WO-1996040640-A1 | BIPHENYL-2-CARBOXYLIC ACID-TETRAHYDRO-ISOQUINOLIN-6-YL AMIDE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MICROSOMAL TRIGLYCERIDE TRANSFER PROTEIN AND/OR APOLIPOPROTEIN B (Apo B) SECRETION | PFIZER INC. (US) | 1996-12-19 | — | — | WO | claimed |
| EP-0106140-B1 | BENZOIC ACID DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1988-08-17 | — | — | EP | claimed |
| EP-0059983-B1 | SUBSTITUTED BIPHENYL COMPOUNDS FOR USE AS A MEDICAMENT | THE WELLCOME FOUNDATION LIMITED (GB) | 1986-06-11 | — | — | EP | claimed |
| EP-0106140-A2 | Benzoic acid derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-04-25 | — | — | EP | claimed |
| EP-0059983-A1 | Substituted biphenyl compounds for use as a medicament | THE WELLCOME FOUNDATION LIMITED (GB) | 1982-09-15 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | CYP2C8 2897/4885KIF11 2590/4885GAA 360/4885 |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | CYP2C8 2897/4885KIF11 2590/4885GAA 360/4885 |
| US-20180105487-A1 | PROCESS FOR THE PREPARATION OF LOMITAPIDE | LIPA, LPAR4, CETP | CYP2C8 1045/4885KIF11 420/4885GAA 611/4885 |
| US-20200190018-A1 | Process For The Preparation of Lomitapide | LIPA, LPAR4, CETP | CYP2C8 1045/4885KIF11 420/4885GAA 611/4885 |
| US-10934251-B2 | Process for the preparation of lomitapide | LIPA, LPAR4, CETP | CYP2C8 1045/4885KIF11 420/4885GAA 611/4885 |
| US-20180282257-A1 | Aromatic Monoester Compositions and Processes for Preparing Same | ADH1A, ADH1C, GK | CYP2C8 127/4885KIF11 1500/4885GAA 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.