Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRB | P28702 | 9/20 | 0.65 |
| ▸ | RXRA | P19793 | 8/20 | 0.65 |
| ▸ | RXRG | P48443 | 7/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13312172 | 0.92 | RXRB (0.66) | RXRBRXRARXRGFFAR1PTGER4 | |
| SCHEMBL13312165 | 0.91 | RXRA (0.65) | RXRBRXRARXRGFFAR1FFAR4 | |
| SCHEMBL3502742 | 0.90 | RXRA (0.53) | RXRBRXRARXRGFFAR1PTGER4 | |
| SCHEMBL13312162 | 0.90 | RXRA (0.63) | RXRBRXRARXRGFFAR1FFAR4 | |
| SCHEMBL13312174 | 0.90 | RXRA (0.63) | RXRBRXRARXRGFFAR1FFAR4 | |
| SCHEMBL13312164 | 0.89 | RXRA (0.67) | RXRBRXRARXRGFFAR1FFAR4 | |
| SCHEMBL13348381 | 0.88 | RXRB (0.49) | RXRBRXRARXRGFFAR1PTGER4 | |
| SCHEMBL13312173 | 0.87 | RXRA (0.69) | RXRBRXRARXRGFFAR1FFAR4 | |
| SCHEMBL13312168 | 0.87 | RXRB (0.64) | RXRBRXRARXRGFFAR1PTGER4 | |
| SCHEMBL13312158 | 0.87 | RXRA (0.64) | RXRBRXRARXRGFFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | RXRB 465/4885RXRA 475/4885RXRG 541/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.