Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6823988 | 0.90 | GAA (0.61) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL20553753 | 0.79 | SMN1; SMN2 (0.50) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL32666095 | 0.78 | SMN1; SMN2 (0.51) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL2678410 | 0.78 | SMN1; SMN2 (0.51) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL9382818 | 0.75 | NAAA (0.50) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL28902235 | 0.75 | KMT2A (0.48) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11308520 | 0.75 | HSD17B10 (0.41) | GAAMEN1KMT2ALMNANPSR1 | |
| SCHEMBL1578826 | 0.74 | ALDH1A1 (0.78) | GAASMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL29904211 | 0.74 | KDM4E (0.44) | GAANPSR1ALDH1A1POLBTSHR | |
| SCHEMBL11480252 | 0.73 | ALDH1A1 (0.81) | GAASMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692126-B1 | REACTIVE CYCLIC CARBONATES AND UREAS USED FOR MODIFYING BIOMOLECULES, POLYMERS, AND SURFACES | HENKEL AG & CO KGAA (DE) | 2012-11-07 | — | — | EP | disclosed |
| US-7728069-B2 | Reactive cyclic carbonates and ureas used for modifying biomolecules, polymers, and surfaces | HENKEL AG & CO. KGAA (DE) | 2010-06-01 | — | — | US | disclosed |
| US-7728069-B2 | Reactive cyclic carbonates and ureas used for modifying biomolecules, polymers, and surfaces | HENKEL AG & CO. KGAA (DE) | 2010-06-01 | — | — | US | disclosed |
| US-20070092656-A1 | Reactive cyclic carbonates and ureas used for modifying biomolecules, polymers, and surfaces | DEUTSCHES WOLLFORSCHUNGSINSTITUT AN DER RWTH AACHEN E.V. (DE) | 2007-04-26 | — | — | US | disclosed |
| US-20070092656-A1 | Reactive cyclic carbonates and ureas used for modifying biomolecules, polymers, and surfaces | DEUTSCHES WOLLFORSCHUNGSINSTITUT AN DER RWTH AACHEN E.V. (DE) | 2007-04-26 | — | — | US | disclosed |