Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.50 |
| ▸ | FAAH | O00519 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378454 | 0.90 | NAAA (0.60) | NAAAFAAHKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2678410 | 0.78 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2NPC1CHRNA7HTR3A | |
| SCHEMBL20553753 | 0.76 | SMN1; SMN2 (0.50) | KMT2ASMN1; SMN2NPC1CHRNA7HTR3A | |
| SCHEMBL16416569 | 0.75 | PIK3CD (0.41) | NAAAFAAH | |
| SCHEMBL13313066 | 0.75 | GAA (0.51) | KMT2ASMN1; SMN2NPC1CHRNA7HTR3A | |
| SCHEMBL32666095 | 0.75 | SMN1; SMN2 (0.51) | KMT2ASMN1; SMN2NPC1CHRNA7HTR3A | |
| SCHEMBL1668216 | 0.73 | NAAA (0.45) | NAAAFAAHKMT2AALDH1A1KDM4E | |
| SCHEMBL28902235 | 0.72 | KMT2A (0.48) | KMT2ASMN1; SMN2NPC1CHRNA7HTR3A | |
| SCHEMBL22450120 | 0.72 | GAA (0.55) | KMT2ASMN1; SMN2NPC1CHRNA7HTR3A | |
| SCHEMBL6823988 | 0.71 | GAA (0.61) | KMT2ASMN1; SMN2NPC1CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0401707-B1 | Heterocyclic triazin or triazolo compounds having serotonin 2-receptor antagonistic activity | DAIICHI SEIYAKU CO (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5232924-A | Cardiovascular disorders | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0401707-A1 | Heterocyclic triazin or triazolo compounds having serotonin 2-receptor antagonistic activity | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1990-12-12 | — | — | EP | disclosed |