Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | ACE | P12821 | 2/20 | 0.57 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | CPA1 | P15085 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | LAP3 | P28838 | 1/20 | 0.54 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.53 |
| ▸ | YAP1 | P46937 | 1/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052952 | 0.91 | PPARG (0.69) | PPARGACEGPR34ITGB3ITGA2B | |
| SCHEMBL13647811 | 0.91 | GPR34 (0.58) | PPARGACEGPR34MMECPA1 | |
| SCHEMBL13296314 | 0.91 | GPR34 (0.58) | PPARGACEGPR34MMECPA1 | |
| SCHEMBL5966590 | 0.84 | LPAR1 (0.65) | PPARGITGB3ITGA2BLPAR1LPAR3 | |
| SCHEMBL8390536 | 0.84 | BCL2 (0.52) | PPARGACEGPR34ITGB3ITGA2B | |
| SCHEMBL8418254 | 0.83 | MMP9 (0.61) | PPARGACEGPR34ITGB3ITGA2B | |
| SCHEMBL8418262 | 0.83 | MMP9 (0.61) | PPARGACEGPR34ITGB3ITGA2B | |
| SCHEMBL25901510 | 0.83 | MME (0.62) | PPARGACEGPR34MMECPA1 | |
| SCHEMBL23901567 | 0.83 | LTA4H (0.61) | PPARGACEGPR34MMECPA1 | |
| SCHEMBL9488674 | 0.82 | TP53 (0.59) | ACEMMP8TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732416-B2 | For protecting plants against parasitic feeding pests; also against the infestation of pets, especially cats and dogs, by fleas, ticks and nematodes; pesticides for crop protection | MERIAL LIMITED (US) | 2010-06-08 | — | — | US | disclosed |