Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 6/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | LAP3 | P28838 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | CPA1 | P15085 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.53 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418254 | 1.00 | MMP9 (0.61) | MMP9MMP8PPARGLTA4HLAP3 | |
| SCHEMBL14064316 | 0.89 | TACR1 (0.55) | MMP9MMP8MAPTS1PR1ACE | |
| SCHEMBL23901567 | 0.87 | LTA4H (0.61) | MMP9MMP8PPARGLTA4HLAP3 | |
| SCHEMBL13296314 | 0.85 | GPR34 (0.58) | MMP9MMP8PPARGLTA4HLAP3 | |
| SCHEMBL25901510 | 0.85 | MME (0.62) | MMP9MMP8PPARGLTA4HLAP3 | |
| SCHEMBL25093130 | 0.85 | PPARG (0.60) | MMP9MMP8PPARGLTA4HMME | |
| SCHEMBL13647811 | 0.85 | GPR34 (0.58) | MMP9MMP8PPARGLTA4HLAP3 | |
| SCHEMBL13314871 | 0.83 | PPARG (0.58) | MMP9MMP8PPARGLTA4HLAP3 | |
| SCHEMBL30538862 | 0.83 | LTA4H (0.61) | MMP9MMP8PPARGLTA4HLAP3 | |
| SCHEMBL18171823 | 0.83 | TACR1 (0.62) | MAPTS1PR1ACETACR1MBTPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922697-A | Compounds, compositions and methods for inhibiting the binding of proteins containing an SH2 domain to cognate phosphorylated proteins | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |