Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 12/20 | 0.48 |
| ▸ | MEN1 | O00255 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | USP2 | O75604 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13315799 | 0.90 | MAPT (0.58) | ADRA1DADRA1AADRA1BCYP19A1MAPT | |
| SCHEMBL3550061 | 0.90 | MAPT (0.60) | ADRA1DADRA1AADRA1BCYP19A1MAPT | |
| SCHEMBL13315798 | 0.86 | CA12 (0.45) | ADRA1DADRA1AADRA1BCYP19A1MAPT | |
| SCHEMBL12527306 | 0.86 | MAPT (0.45) | ADRA1DADRA1AADRA1BCYP19A1MAPT | |
| SCHEMBL12496090 | 0.85 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BCYP19A1MAPT | |
| SCHEMBL12494762 | 0.85 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BCYP19A1MAPT | |
| SCHEMBL10069265 | 0.82 | ADRA1A (0.35) | ADRA1DADRA1AADRA1BMAPTALDH1A1 | |
| SCHEMBL30425863 | 0.82 | PGR (0.47) | ADRA1DADRA1AADRA1BALDH1A1KDM4E | |
| SCHEMBL13315800 | 0.82 | MAPT (0.52) | ADRA1DADRA1AADRA1BCYP19A1MAPT | |
| SCHEMBL13315801 | 0.82 | CYP19A1 (0.51) | ADRA1DADRA1AADRA1BCYP19A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152431-A1 | COMPOSITIONS, PROBES AND CONJUGATES AND USES THEREOF | THIRD WAVE TECHNOLOGIES, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-7674924-B2 | Compositions, probes, and conjugates and uses thereof | THIRD WAVE TECHNOLOGIES, INC. (US) | 2010-03-09 | — | — | US | disclosed |
| US-20080071074-A1 | Compositions, probes, and conjugates and uses thereof | THIRD WAVE TECHNOLOGIES, INC. (US) | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152431-A1 | COMPOSITIONS, PROBES AND CONJUGATES AND USES THEREOF | ALKBH1, DUT, NT5E | ADRA1D 2150/4885ADRA1A 2143/4885ADRA1B 2052/4885 |
| US-20080071074-A1 | Compositions, probes, and conjugates and uses thereof | ALKBH1, ALK, DUT | ADRA1D 1749/4885ADRA1A 1771/4885ADRA1B 1802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.