Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.31 |
| ▸ | CFD | P00746 | 1/20 | 0.31 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13316636 | 0.90 | PDE3B (0.40) | PDE3BPDE3ATP53KDM4EUSP2 | |
| SCHEMBL3621739 | 0.84 | METTL3 (0.38) | METTL3PCSK9MAPTTP53KDM4E | |
| SCHEMBL13349670 | 0.78 | PCSK9 (0.33) | METTL3PCSK9ALDH1A1 | |
| SCHEMBL13316635 | 0.77 | PDE3B (0.36) | PDE3BPDE3ATP53KDM4EUSP2 | |
| SCHEMBL3627969 | 0.76 | PDE3B (0.41) | METTL3PDE3BPDE3AMAPTKDM4E | |
| SCHEMBL3620368 | 0.70 | PDE3B (0.43) | PDE3BPDE3AMAPTKDM4EUSP2 | |
| SCHEMBL3623959 | 0.70 | METTL3 (0.41) | METTL3CFD | |
| SCHEMBL13316623 | 0.69 | METTL3 (0.40) | METTL3KLKB1PDE3BPDE3ACFD | |
| SCHEMBL13316622 | 0.69 | PDE3B (0.41) | PDE3BPDE3AKDM4EUSP2ALDH1A1 | |
| SCHEMBL13349668 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745459-B2 | Quinolizinone compound and use thereof as HIV integrase inhibitor | JAPAN TOBACCO INC. (JP) | 2010-06-29 | — | — | US | disclosed |