Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574069 | 0.90 | SMN1; SMN2 (0.53) | SMN1; SMN2DRD2DRD4KDM4EMAPK1 | |
| SCHEMBL3576228 | 0.84 | ALDH1A1 (0.43) | SMN1; SMN2DRD2DRD4KDM4EMAPK1 | |
| SCHEMBL3585190 | 0.81 | SMN1; SMN2 (0.52) | SMN1; SMN2DRD2DRD4MAPK1 | |
| SCHEMBL13316669 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPK1TDP1L3MBTL1POLB | |
| SCHEMBL3577900 | 0.75 | RAB9A (0.47) | SMN1; SMN2MAPK1HPGDL3MBTL1 | |
| SCHEMBL3566335 | 0.75 | SMN1; SMN2 (0.51) | SMN1; SMN2KDM4EMAPK1L3MBTL1POLB | |
| SCHEMBL3581797 | 0.73 | DRD2 (0.55) | SMN1; SMN2DRD2DRD4TDP1L3MBTL1 | |
| SCHEMBL5686017 | 0.72 | DRD2 (0.72) | SMN1; SMN2DRD2DRD4KDM4EMAPK1 | |
| SCHEMBL2063136 | 0.72 | DRD2 (0.72) | SMN1; SMN2DRD2DRD4KDM4EMAPK1 | |
| SCHEMBL3580415 | 0.71 | KMT2A (0.52) | SMN1; SMN2KDM4EMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728005-B2 | Ether derivative | AJINOMOTO CO., INC. (JP) | 2010-06-01 | — | — | US | disclosed |