Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.68 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.68 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.68 |
| ▸ | GRM6 | O15303 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | GRM8 | O00222 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | GRM5 | P41594 | 1/20 | 0.68 |
| ▸ | MTOR | P42345 | 1/20 | 0.68 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.68 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063416 | 1.00 | CYP1A2 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL1263461 | 1.00 | CYP1A2 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL2157698 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL235442 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL179741 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL719389 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL481144 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL4835874 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL935371 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL3125919 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486892-B2 | Blood coagulation factor inhibitors | NOVO NORDISK HEALTH CARE AG (CH) | 2013-07-16 | — | — | US | claimed |
| US-20110229453-A1 | BLOOD COAGULATION FACTOR INHIBITORS | NOVO NORDISK HEALTH CARE AG (CH) | 2011-09-22 | — | — | US | claimed |
| US-20110003752-A1 | New Blood Coagulation Factor Inhibitors | NOVO NORDISK HEALTH CARE A/G (CH) | 2011-01-06 | — | — | US | claimed |
| JP-2010536824-A | — | — | 2010-12-02 | — | — | JP | claimed |
| EP-2235042-A1 | NEW BLOOD COAGULATION FACTOR INHIBITORS | Novo Nordisk Health Care AG (CH) | 2010-10-06 | — | — | EP | claimed |
| EP-2190860-A1 | BLOOD COAGULATION FACTOR INHIBITORS | Novo Nordisk Health Care AG (CH) | 2010-06-02 | — | — | EP | claimed |
| WO-2009092758-A1 | NEW BLOOD COAGULATION FACTOR INHIBITORS | NOVO NORDISK HEALTH CARE AG (DK) | 2009-07-30 | — | — | WO | claimed |
| WO-2009024571-A1 | BLOOD COAGULATION FACTOR INHIBITORS | NOVO NORDISK HEALTH CARE AG (DK) | 2009-02-26 | — | — | WO | claimed |
| US-8961931-B2 | 18F-labeled monomeric galactose derivative used as tomography probe | INSTITUTE OF NUCLEAR ENERGY RESEARCH, ATOMIC ENERGY COUNCIL (TW) | 2015-02-24 | — | — | US | disclosed |
| US-8569481-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PHARMACEUTICALS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8486892-B2 | Blood coagulation factor inhibitors | NOVO NORDISK HEALTH CARE AG (CH) | 2013-07-16 | — | — | US | disclosed |
| US-20120259102-A1 | 18F-Labeled Monomeric Galactose Derivative Used as Tomography Probe | ATOMIC ENERGY COUNCIL-INSTITUTE OF NUCLEAR ENERGY RESEARCH (TW) | 2012-10-11 | — | — | US | disclosed |
| US-20110229453-A1 | BLOOD COAGULATION FACTOR INHIBITORS | NOVO NORDISK HEALTH CARE AG (CH) | 2011-09-22 | — | — | US | disclosed |
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | KOESTER HUBERT | 2011-05-19 | — | — | US | disclosed |
| US-5658782-A | AN ISOLATED NUCLEIC ACID COMPRISING A NUCLEOTIDE SEQUENCE ENCODING A HUMAN EXCITATORY AMINO ACID TRANSPORTER PROTEIN; GENETIC ENGINEERING | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY A NON-PROFIT ORGANIZATION (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0724637-A1 | CORTICOTROPIN-RELEASING FACTOR 2 RECEPTORS | NEUROCRINE BIOSCIENCES, INC. (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995034651-A2 | CORTICOTROPIN-RELEASING FACTOR2 RECEPTORS | NEUROCRINE BIOSCIENCES, INC. (US) | 1995-12-21 | — | — | WO | disclosed |
| EP-0610336-A1 | TREATMENT OF NEUROLOGICAL CONDITIONS BY AN INTERLEUKIN-1 INHIBITING COMPOUND | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993008819-A1 | TREATMENT OF NEUROLOGICAL CONDITIONS BY AN INTERLEUKIN-1 INHIBITING COMPOUND | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1993-05-13 | — | — | WO | disclosed |
| WO-1993008820-A1 | TREATMENT OF NEUROLOGICAL CONDITIONS BY AN INTERLEUKIN-1 INHIBITING COMPOUND | THE VICTORIA UNIVERSITY OF MANCHESTER (GB) | 1993-05-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120259102-A1 | 18F-Labeled Monomeric Galactose Derivative Used as Tomography Probe | UGGT1, GALK1, GALE | CYP1A2 2134/4885ALOX15 3639/4885ALDH1A1 960/4885 |
| US-20110003752-A1 | New Blood Coagulation Factor Inhibitors | F7, F12, F5 | CYP1A2 1341/4885ALOX15 1914/4885ALDH1A1 4724/4885 |
| US-20110118136-A1 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PTMS, QPCTL, SRMS | CYP1A2 4732/4885ALOX15 4508/4885ALDH1A1 4360/4885 |
| US-20110229453-A1 | BLOOD COAGULATION FACTOR INHIBITORS | F5, TFPI, F7 | CYP1A2 492/4885ALOX15 1124/4885ALDH1A1 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.