SCHEMBL1263461

SCHEMBL1263461

NC1(C(=O)O)CC(C(=O)O)C1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 4/20 1.00
▸ ALOX15 P16050 3/20 1.00
▸ ALDH1A1 P00352 2/20 1.00
▸ KDM4E B2RXH2 1/20 1.00
▸ GRM4 Q14833 6/20 0.68
▸ GRM2 Q14416 5/20 0.68
▸ GRM3 Q14832 5/20 0.68
▸ CYP2C19 P33261 4/20 0.68
▸ GRM6 O15303 3/20 0.68
▸ TDP1 Q9NUW8 2/20 0.68
▸ GRM8 O00222 2/20 0.68
▸ LMNA P02545 1/20 0.68
▸ GRM5 P41594 1/20 0.68
▸ MTOR P42345 1/20 0.68
▸ GRM1 Q13255 1/20 0.68
▸ PLCB1 Q9NQ66 1/20 0.68
▸ TSHR P16473 1/20 0.68
▸ MEN1 O00255 1/20 0.65
▸ KMT2A Q03164 1/20 0.65
▸ CYP2D6 P10635 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1063416 1.00 CYP1A2 (1.00) CYP1A2ALOX15ALDH1A1KDM4EGRM4
SCHEMBL1064244 1.00 CYP1A2 (1.00) CYP1A2ALOX15ALDH1A1KDM4EGRM4
SCHEMBL719389 0.81 GRM4 (1.00) CYP1A2ALOX15ALDH1A1KDM4EGRM4
SCHEMBL4835874 0.81 GRM4 (1.00) CYP1A2ALOX15ALDH1A1KDM4EGRM4
SCHEMBL179741 0.81 GRM4 (1.00) CYP1A2ALOX15ALDH1A1KDM4EGRM4
SCHEMBL481144 0.81 GRM4 (1.00) CYP1A2ALOX15ALDH1A1KDM4EGRM4
SCHEMBL2157698 0.81 GRM4 (1.00) CYP1A2ALOX15ALDH1A1KDM4EGRM4
SCHEMBL935371 0.81 GRM4 (1.00) CYP1A2ALOX15ALDH1A1KDM4EGRM4
SCHEMBL235442 0.81 GRM4 (1.00) CYP1A2ALOX15ALDH1A1KDM4EGRM4
SCHEMBL3125919 0.81 GRM4 (1.00) CYP1A2ALOX15ALDH1A1KDM4EGRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552733-B2 Terpenophenolic compounds and their use PHYTOTHERAPEUTIX LIMITED (GB) 2026-02-17 — — US claimed
US-20230225985-A1 TERPENOPHENOLIC COMPOUNDS AND THEIR USE PHYTOTHERAPEUTIX LIMITED (GB) 2023-07-20 — — US claimed
US-20230227390-A1 TERPENOPHENOLIC COMPOUNDS AND THEIR USE PHYTOTHERAPEUTIX LIMITED (GB) 2023-07-20 — — US claimed
CN-116194431-A Terpene phenol compound and application thereof 植物疗法有限公司 2023-05-30 — — CN claimed
CN-101981050-A New blood coagulation factor inhibitors NOVO NORDISK HEALTHCARE AG 2011-02-23 — — CN claimed
EP-1952797-A1 Use of a cosmetic composition comprising NMDA receptor agonists for cosmetic skin treatment Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) 2008-08-06 — — EP claimed
EP-1800672-A1 Pharmaceutical composition and the use therof for the treatment of dermatoses Dr. August Wolff GmbH & Co. (DE) 2007-06-27 — — EP claimed
US-12606508-B2 Cannabis extracts and uses thereof CONSIGLIO NAZIONALE DELLE RICERCHE (IT) 2026-04-21 — — US disclosed
US-20260072008-A1 METHOD OF CHARACTERISING A PEPTIDE, POLYPEPTIDE OR PROTEIN USING A NANOPORE UNIV OXFORD INNOVATION LTD (GB) 2026-03-12 — — US disclosed
US-12552733-B2 Terpenophenolic compounds and their use PHYTOTHERAPEUTIX LIMITED (GB) 2026-02-17 — — US disclosed
EP-4662489-A1 METHOD OF CHARACTERISING A PEPTIDE, POLYPEPTIDE OR PROTEIN USING A NANOPORE Oxford University Innovation Limited (GB) 2025-12-17 — — EP disclosed
EP-4626438-A2 INHALABLE HORMONE RECEPTOR AGONIST FORMULATIONS Pinata Holdings Inc. (US) 2025-10-08 — — EP disclosed
WO-2025022003-A1 BETA-PEPTIDES WITH CYTOTOXIC ACTIVITY ON CANCER CELLS Universität Linz (AT) 2025-01-30 — — WO disclosed
US-5919628-A Amino acid transporters and uses OREGON HEALTH SCIENCES UNIVERSITY (US) 1999-07-06 — — US disclosed
US-5840516-A SCREENING COMPOUNDS AS AN INHIBITOR OF EXCITATORY AMINO ACID TRANSPORT IN CELLS, TRANSFORMING CELL CULTURE FOR GENETIC EXPRESSION, ANALYZING TRANSFORMED CELL CULTURE STATE OF OREGON (US) 1998-11-24 — — US disclosed
US-5776774-A Amino acid transporters and uses STATE OF OREGON (US) 1998-07-07 — — US disclosed
US-5658782-A AN ISOLATED NUCLEIC ACID COMPRISING A NUCLEOTIDE SEQUENCE ENCODING A HUMAN EXCITATORY AMINO ACID TRANSPORTER PROTEIN; GENETIC ENGINEERING STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY A NON-PROFIT ORGANIZATION (US) 1997-08-19 — — US disclosed
EP-0610336-A1 TREATMENT OF NEUROLOGICAL CONDITIONS BY AN INTERLEUKIN-1 INHIBITING COMPOUND THE VICTORIA UNIVERSITY OF MANCHESTER (GB) 1994-08-17 — — EP disclosed
WO-1993008820-A1 TREATMENT OF NEUROLOGICAL CONDITIONS BY AN INTERLEUKIN-1 INHIBITING COMPOUND THE VICTORIA UNIVERSITY OF MANCHESTER (GB) 1993-05-13 — — WO disclosed
WO-1993008819-A1 TREATMENT OF NEUROLOGICAL CONDITIONS BY AN INTERLEUKIN-1 INHIBITING COMPOUND THE VICTORIA UNIVERSITY OF MANCHESTER (GB) 1993-05-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260072008-A1 METHOD OF CHARACTERISING A PEPTIDE, POLYPEPTIDE OR PROTEIN USING A NANOPORE MAX, NPPA, NUP210 CYP1A2 4846/4885ALOX15 4473/4885ALDH1A1 4882/4885
US-20230225985-A1 TERPENOPHENOLIC COMPOUNDS AND THEIR USE TPMT, MALT1, UGT1A1 CYP1A2 42/4885ALOX15 1873/4885ALDH1A1 484/4885
US-12606508-B2 Cannabis extracts and uses thereof CNR1, CNR2, FAAH CYP1A2 364/4885ALOX15 604/4885ALDH1A1 723/4885
US-20230227390-A1 TERPENOPHENOLIC COMPOUNDS AND THEIR USE TPMT, MALT1, UGT1A1 CYP1A2 43/4885ALOX15 1935/4885ALDH1A1 484/4885
US-12552733-B2 Terpenophenolic compounds and their use TPMT, MALT1, CNR1 CYP1A2 70/4885ALOX15 2151/4885ALDH1A1 613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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