Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.68 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.68 |
| ▸ | GRM3 | Q14832 | 5/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.68 |
| ▸ | GRM6 | O15303 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | GRM8 | O00222 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | GRM5 | P41594 | 1/20 | 0.68 |
| ▸ | MTOR | P42345 | 1/20 | 0.68 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.68 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263461 | 1.00 | CYP1A2 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL1064244 | 1.00 | CYP1A2 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL719389 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL4835874 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL179741 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL481144 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL2157698 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL935371 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL235442 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 | |
| SCHEMBL3125919 | 0.81 | GRM4 (1.00) | CYP1A2ALOX15ALDH1A1KDM4EGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486892-B2 | Blood coagulation factor inhibitors | NOVO NORDISK HEALTH CARE AG (CH) | 2013-07-16 | — | — | US | claimed |
| US-20110229453-A1 | BLOOD COAGULATION FACTOR INHIBITORS | NOVO NORDISK HEALTH CARE AG (CH) | 2011-09-22 | — | — | US | claimed |
| US-20110003752-A1 | New Blood Coagulation Factor Inhibitors | NOVO NORDISK HEALTH CARE A/G (CH) | 2011-01-06 | — | — | US | claimed |
| JP-2010536824-A | — | — | 2010-12-02 | — | — | JP | claimed |
| EP-2235042-A1 | NEW BLOOD COAGULATION FACTOR INHIBITORS | Novo Nordisk Health Care AG (CH) | 2010-10-06 | — | — | EP | claimed |
| EP-2190860-A1 | BLOOD COAGULATION FACTOR INHIBITORS | Novo Nordisk Health Care AG (CH) | 2010-06-02 | — | — | EP | claimed |
| WO-2009092758-A1 | NEW BLOOD COAGULATION FACTOR INHIBITORS | NOVO NORDISK HEALTH CARE AG (DK) | 2009-07-30 | — | — | WO | claimed |
| WO-2009024571-A1 | BLOOD COAGULATION FACTOR INHIBITORS | NOVO NORDISK HEALTH CARE AG (DK) | 2009-02-26 | — | — | WO | claimed |
| US-20190274334-A1 | COMPOUNDS THAT MODULATE CALCIUM-SENSING RECEPTOR ACTIVITY FOR MODULATING KOKUMI TASTE AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2019-09-12 | — | — | US | disclosed |
| US-20190274334-A1 | COMPOUNDS THAT MODULATE CALCIUM-SENSING RECEPTOR ACTIVITY FOR MODULATING KOKUMI TASTE AND PET FOOD PRODUCTS CONTAINING THE SAME | MARS, INCORPORATED (US) | 2019-09-12 | — | — | US | disclosed |
| US-9034798-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | CAPROTEC BIOANALYTICS GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-8569481-B2 | Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions | PHARMACEUTICALS, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-8486892-B2 | Blood coagulation factor inhibitors | NOVO NORDISK HEALTH CARE AG (CH) | 2013-07-16 | — | — | US | disclosed |
| US-20110229453-A1 | BLOOD COAGULATION FACTOR INHIBITORS | NOVO NORDISK HEALTH CARE AG (CH) | 2011-09-22 | — | — | US | disclosed |
| US-20060135480-A1 | Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex | ENOBIA PHARMA (CA) | 2006-06-22 | — | — | US | disclosed |
| EP-1572645-A2 | DERIVATIVES OF SUCCINIC AND GLUTARIC ACIDS AND ANALOGS THEREOF USEFUL AS INHIBITORS OF PHEX | Enobia Pharma Inc. (CA) | 2005-09-14 | — | — | EP | disclosed |
| US-20040186301-A1 | Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex | BIOMEP INC. | 2004-09-23 | — | — | US | disclosed |
| WO-2004050620-A2 | DERIVATIVES OF SUCCINIC AND GLUTARIC ACIDS AND ANALOGS THEREOF USEFUL AS INHIBITORS OF PHEX | ENOBIA PHARMA (CA) | 2004-06-17 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003752-A1 | New Blood Coagulation Factor Inhibitors | F7, F12, F5 | CYP1A2 1341/4885ALOX15 1914/4885ALDH1A1 4724/4885 |
| US-20040186301-A1 | Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex | GLS, SUCNR1, PGD | CYP1A2 1550/4885ALOX15 2056/4885ALDH1A1 1271/4885 |
| US-20060135480-A1 | Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex | GLS, SUCNR1, GCDH | CYP1A2 1488/4885ALOX15 1969/4885ALDH1A1 1091/4885 |
| US-20110229453-A1 | BLOOD COAGULATION FACTOR INHIBITORS | F5, TFPI, F7 | CYP1A2 492/4885ALOX15 1124/4885ALDH1A1 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.