Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.67 |
| ▸ | PNP | P00491 | 2/20 | 0.67 |
| ▸ | THPO | P40225 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | EIF4E | P06730 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | TOP1 | P11387 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | GMNN | O75496 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.59 |
| ▸ | MTOR | P42345 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13352202 | 1.00 | LMNA (0.67) | LMNASMN1; SMN2ALDH1A1ADORA1PNP | |
| SCHEMBL13352186 | 0.82 | LMNA (0.64) | LMNASMN1; SMN2ALDH1A1ADORA1PNP | |
| SCHEMBL13320550 | 0.82 | LMNA (0.64) | LMNASMN1; SMN2ALDH1A1ADORA1PNP | |
| SCHEMBL14147782 | 0.82 | LMNA (0.64) | LMNASMN1; SMN2ALDH1A1ADORA1PNP | |
| SCHEMBL13320578 | 0.82 | LMNA (0.63) | LMNASMN1; SMN2ALDH1A1ADORA1PNP | |
| SCHEMBL13352203 | 0.82 | LMNA (0.63) | LMNASMN1; SMN2ALDH1A1ADORA1PNP | |
| SCHEMBL3463215 | 0.82 | LMNA (0.63) | LMNASMN1; SMN2ALDH1A1ADORA1PNP | |
| SCHEMBL13352204 | 0.82 | LMNA (0.63) | LMNASMN1; SMN2ALDH1A1ADORA1PNP | |
| SCHEMBL15171052 | 0.82 | LMNA (0.63) | LMNASMN1; SMN2ALDH1A1ADORA1PNP | |
| SCHEMBL13320576 | 0.82 | LMNA (0.63) | LMNASMN1; SMN2ALDH1A1ADORA1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100129317-A1 | AZOLE NUCLEOSIDES AND USE AS INHIBITORS OF RNA AND DNA VIRAL POLYMERASES | SOUTHERN RESEARCH INSTITUTE (US) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100129317-A1 | AZOLE NUCLEOSIDES AND USE AS INHIBITORS OF RNA AND DNA VIRAL POLYMERASES | RNASEH1, RNASEL, POLR2E | LMNA 739/4885SMN1; SMN2 3616/4885ALDH1A1 2684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.