SCHEMBL13320657

SCHEMBL13320657

CC(=O)[C@@H](N)CCCCNC(=N)N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.46
GNAI3 P08754 1/20 0.44
GNAO1 P09471 1/20 0.44
GNAI1 P63096 1/20 0.44
ALOX15 P16050 1/20 0.41
CYP1A2 P05177 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
RRM1 P23921 1/20 0.39
NPY4R P50391 4/20 0.38
NPY1R P25929 3/20 0.38
NPY2R P49146 2/20 0.38
NPY5R Q15761 2/20 0.38
NOS2 P35228 5/20 0.38
NOS1 P29475 4/20 0.38
NOS3 P29474 3/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10190380 1.00 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1ALOX15
SCHEMBL16421890 1.00 DPP7 (0.46) DPP7GNAI3GNAO1GNAI1ALOX15
SCHEMBL10292018 0.95 DPP7 (0.43) DPP7GNAI3GNAO1GNAI1ALOX15
SCHEMBL8745865 0.95 DPP7 (0.43) DPP7GNAI3GNAO1GNAI1ALOX15
SCHEMBL8214683 0.95 DPP7 (0.43) DPP7GNAI3GNAO1GNAI1ALOX15
SCHEMBL8067808 0.87 DPP7 (0.47) DPP7GNAI3GNAO1GNAI1CYP1A2
SCHEMBL12278048 0.87 ANPEP (0.37) DPP7GNAI3GNAO1GNAI1ALOX15
SCHEMBL13434929 0.87 ANPEP (0.37) DPP7GNAI3GNAO1GNAI1ALOX15
SCHEMBL8125131 0.87 ANPEP (0.37) DPP7GNAI3GNAO1GNAI1ALOX15
SCHEMBL26431362 0.85 DPP7 (0.49) DPP7GNAI3GNAO1GNAI1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240010627-A1 NOVEL GUANIDINE DERIVATIVE AND METHOD FOR PRODUCING SAME PEPTIDREAM INC. (JP) 2024-01-11 US disclosed
EP-4276096-A1 NOVEL GUANIDINE DERIVATIVE AND METHOD FOR PRODUCING SAME PeptiDream Inc. (JP) 2023-11-15 EP disclosed
WO-2023072971-A2 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B PHARMACEUTICALS GMBH (DE) 2023-05-04 WO disclosed
EP-4170347-A1 GASTRIC INHIBITORY PEPTIDE RECEPTOR LIGANDS 3B Pharmaceuticals GmbH (DE) 2023-04-26 EP disclosed
WO-2022149610-A1 NOVEL GUANIDINE DERIVATIVE AND METHOD FOR PRODUCING SAME ペプチドリーム株式会社 2022-07-14 WO disclosed
US-20170304355-A1 COMPOSITIONS AND METHODS OF USE THEREOF SYNEDGEN, INC. (US) 2017-10-26 US disclosed
US-20170136056-A1 METHODS AND COMPOSITIONS FOR DISRUPTING BIOFILM UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS UNITED STATES GOVERNMENT 2017-05-18 US disclosed
US-20150031610-A1 DERIVATIZED POLYGLUCOSAMINES FOR DELIVERY OF SMALL MOLECULES, PEPTIDES, AND PROTEINS SYNEDGEN, INC. 2015-01-29 US disclosed
US-8399635-B2 Chitosan derivatives to treat animals or optimize animal health SYNEDGEN, INC. (US) 2013-03-19 US disclosed
US-20100137193-A1 CHITOSAN DERIVATIVES TO TREAT ANIMALS OR OPTIMIZE ANIMAL HEALTH SYNEDGEN INC. (US) 2010-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170136056-A1 METHODS AND COMPOSITIONS FOR DISRUPTING BIOFILM UTILIZING CHITOSAN-DERIVATIVE COMPOUNDS CHIT1, ALG1, DDOST DPP7 621/4885GNAI3 2126/4885GNAO1 2313/4885
US-20100137193-A1 CHITOSAN DERIVATIVES TO TREAT ANIMALS OR OPTIMIZE ANIMAL HEALTH CHIT1, CHIA, ALG1 DPP7 461/4885GNAI3 3171/4885GNAO1 2924/4885
US-20170304355-A1 COMPOSITIONS AND METHODS OF USE THEREOF SI, ENGASE, IDUA DPP7 302/4885GNAI3 2464/4885GNAO1 1862/4885
US-20150031610-A1 DERIVATIZED POLYGLUCOSAMINES FOR DELIVERY OF SMALL MOLECULES, PEPTIDES, AND PROTEINS MUC1, DDOST, EPCAM DPP7 341/4885GNAI3 628/4885GNAO1 1624/4885
US-20240010627-A1 NOVEL GUANIDINE DERIVATIVE AND METHOD FOR PRODUCING SAME GMPS, MAPT, UROD DPP7 2455/4885GNAI3 617/4885GNAO1 195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.