SCHEMBL8214683

SCHEMBL8214683

CC(=O)[C@@H](N)CCCNC(=N)N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.43
NPY4R P50391 7/20 0.39
NPY1R P25929 5/20 0.39
NPY2R P49146 4/20 0.39
NPY5R Q15761 4/20 0.39
OTC P00480 1/20 0.39
ALOX15 P16050 1/20 0.39
GNAI3 P08754 1/20 0.38
GNAO1 P09471 1/20 0.38
GNAI1 P63096 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CYP1A2 P05177 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NOS3 P29474 3/20 0.38
NOS1 P29475 3/20 0.38
NOS2 P35228 3/20 0.38
DDAH1 O94760 1/20 0.37
RRM1 P23921 1/20 0.37
CYP2C19 P33261 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8745865 1.00 DPP7 (0.43) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL10292018 1.00 DPP7 (0.43) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL16421890 0.95 DPP7 (0.46) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL10190380 0.95 DPP7 (0.46) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL13320657 0.95 DPP7 (0.46) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL13434929 0.89 ANPEP (0.37) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL12278048 0.89 ANPEP (0.37) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL8125131 0.89 ANPEP (0.37) DPP7NPY4RNPY1RNPY2RNPY5R
SCHEMBL18542868 0.87 DPP7 (0.44) DPP7OTCGNAI3GNAO1GNAI1
SCHEMBL19368710 0.87 DPP7 (0.44) DPP7OTCGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382344-A1 Soluble GLP1/GIP/NPY2 Receptor Triple Agonists BOEHRINGER INGELHEIM INT GMH (DE) 2025-12-18 US claimed
US-20240209026-A1 A4B7 THIOETHER PEPTIDE DIMER ANTAGONISTS PROTAGONIST THERAPEUTICS, INC. (US) 2024-06-27 US claimed
US-20220162261-A1 NOVEL a4B7 PEPTIDE MONOMER AND DIMER ANTAGONISTS PROTAGONIST THERAPEUTICS, INC. 2022-05-26 US claimed
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-04-30 US disclosed
EP-4706671-A2 CONJUGATED HEPCIDIN MIMETICS Protagonist Therapeutics, Inc. (US) 2026-03-11 EP disclosed
EP-3570864-B1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-02-18 EP disclosed
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases PROTAGONIST THERAPEUTICS, INC. (US) 2026-02-17 US disclosed
US-20250382344-A1 Soluble GLP1/GIP/NPY2 Receptor Triple Agonists BOEHRINGER INGELHEIM INT GMH (DE) 2025-12-18 US disclosed
US-20250361280-A1 CONJUGATED HEPCIDIN MIMETICS PROTAGONIST THERAPEUTICS INC (US) 2025-11-27 US disclosed
EP-4025592-B1 CONJUGATED HEPCIDIN MIMETICS FOR USE IN TREATING OF POLYCYTHEMIA VERA PROTAGONIST THERAPEUTICS INC (US) 2025-10-29 EP disclosed
EP-4613761-A9 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES Janssen Biotech, Inc. (US) 2025-10-22 EP disclosed
US-20090270457-A1 6,11-BICYCLOLIDES: BRIDGED BIARYL MACROLIDE DERIVATIVES ENANTA PHARMACEUTICALS, INC. 2009-10-29 US disclosed
US-20090264380-A1 6,11-BRIDGED BIARYL MACROLIDES ENANTA PHARMACEUTICALS, INC. 2009-10-22 US disclosed
US-20090118506-A1 6,11-BRIDGED BIARYL MACROLIDES ENANTA PHARMACEUTICALS, INC. 2009-05-07 US disclosed
US-20090075915-A1 6,11-BICYCLOLIDES: BRIDGED BIARYL MACROLIDE DERIVATIVES ENANTA PHARMACEUTICALS, INC. 2009-03-19 US disclosed
WO-2008040979-A1 ARGININE DERIVATIVES WITH NP-I ANTAGONISTIC ACTIVITY ARK THERAPEUTICS LTD. (GB) 2008-04-10 WO disclosed
US-20070281904-A1 Chitosan-derivative compounds and methods of controlling microbial populations UNITED STATES GOVERNMENT 2007-12-06 US disclosed
US-7176214-B2 Imidazo-fused oxazolo[4,5-β]pyridine and imidazo-fused thiazolo[4,5-β]pyridine based tricyclic compounds and pharmaceutical compositions comprising same BRISTOL-MYERS SQUIBB COMPANY (US) 2007-02-13 US disclosed
EP-0688314-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-27 EP disclosed
WO-1994021604-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090075915-A1 6,11-BICYCLOLIDES: BRIDGED BIARYL MACROLIDE DERIVATIVES CYP2B6, ABCB11, CYP2D6 DPP7 224/4885NPY4R 1784/4885NPY1R 2900/4885
US-20090270457-A1 6,11-BICYCLOLIDES: BRIDGED BIARYL MACROLIDE DERIVATIVES CYP2B6, ABCB11, CYP2D6 DPP7 224/4885NPY4R 1784/4885NPY1R 2900/4885
US-20250361280-A1 CONJUGATED HEPCIDIN MIMETICS HAMP, VIP, HDGF DPP7 737/4885NPY4R 597/4885NPY1R 730/4885
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL17A, IL36G DPP7 826/4885NPY4R 204/4885NPY1R 38/4885
US-20090118506-A1 6,11-BRIDGED BIARYL MACROLIDES CYP2B6, CYP2D6, ABCB11 DPP7 224/4885NPY4R 1567/4885NPY1R 2518/4885
US-20070281904-A1 Chitosan-derivative compounds and methods of controlling microbial populations ARG1, NRDC, CHIA DPP7 305/4885NPY4R 593/4885NPY1R 840/4885
US-20250382344-A1 Soluble GLP1/GIP/NPY2 Receptor Triple Agonists GLP1R, GIPR, NPY1R DPP7 90/4885NPY4R 7/4885NPY1R 3/4885
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, IL36G DPP7 175/4885NPY4R 579/4885NPY1R 61/4885
US-20090264380-A1 6,11-BRIDGED BIARYL MACROLIDES CYP2B6, CYP2D6, ABCB11 DPP7 290/4885NPY4R 943/4885NPY1R 1444/4885
US-20240209026-A1 A4B7 THIOETHER PEPTIDE DIMER ANTAGONISTS EPCAM, ANXA7, GRB7 DPP7 175/4885NPY4R 1132/4885NPY1R 1601/4885
US-20220162261-A1 NOVEL a4B7 PEPTIDE MONOMER AND DIMER ANTAGONISTS EPCAM, VCAM1, ITGB7 DPP7 138/4885NPY4R 630/4885NPY1R 1019/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.