Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | ACE | P12821 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | APAF1 | O14727 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | MPO | P05164 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.62 |
| ▸ | ITGAL | P20701 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30782236 | 0.88 | ALOX15 (0.70) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL170877 | 0.87 | KDM4E (0.69) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL2167226 | 0.87 | ALOX15 (0.68) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL170878 | 0.87 | KDM4E (0.69) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL1755294 | 0.87 | ALOX15 (0.68) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL3857229 | 0.86 | ALOX15 (0.74) | ALOX15ACEITGB2ICAM1ITGAL | |
| Water SCHEMBL5384989 | 0.86 | KDM4E (0.68) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL352261 | 0.86 | SMN1; SMN2 (0.69) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL20816097 | 0.86 | ALOX15 (0.67) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL12583690 | 0.86 | ALOX15 (0.67) | ALOX15ACESMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9673030-B2 | Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry | EMORY UNIVERSITY (US) | 2017-06-06 | — | — | US | disclosed |
| US-20110282587-A1 | COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY | EMORY UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |