SCHEMBL352261

SCHEMBL352261

O=C(O)[C@H](Cc1c[nH]c2ccccc12)NS

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.69
▸ ACE P12821 4/20 0.69
▸ ALOX15 P16050 1/20 0.67
▸ KDM4E B2RXH2 2/20 0.63
▸ MAPT P10636 2/20 0.63
▸ APAF1 O14727 1/20 0.63
▸ POLB P06746 1/20 0.63
▸ RECQL P46063 1/20 0.63
▸ L3MBTL1 Q9Y468 1/20 0.63
▸ MEN1 O00255 1/20 0.63
▸ LMNA P02545 1/20 0.63
▸ MPO P05164 1/20 0.63
▸ TSHR P16473 1/20 0.63
▸ BLM P54132 1/20 0.63
▸ PMP22 Q01453 1/20 0.63
▸ KMT2A Q03164 1/20 0.63
▸ HIF1A Q16665 1/20 0.63
▸ ECE1 P42892 2/20 0.63
▸ ITGB2 P05107 2/20 0.62
▸ ICAM1 P05362 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL352260 1.00 SMN1; SMN2 (0.69) SMN1; SMN2ACEALOX15KDM4EMAPT
SCHEMBL2759204 0.89 SMN1; SMN2 (0.61) SMN1; SMN2ACEALOX15KDM4EMAPT
SCHEMBL30782236 0.88 ALOX15 (0.70) SMN1; SMN2ACEALOX15KDM4EMAPT
SCHEMBL8710933 0.87 SMN1; SMN2 (0.68) SMN1; SMN2ACEALOX15KDM4EMAPT
SCHEMBL8710928 0.87 SMN1; SMN2 (0.68) SMN1; SMN2ACEALOX15KDM4EMAPT
SCHEMBL2167226 0.87 ALOX15 (0.68) SMN1; SMN2ACEALOX15KDM4EMAPT
SCHEMBL1755294 0.87 ALOX15 (0.68) SMN1; SMN2ACEALOX15KDM4EMAPT
SCHEMBL170878 0.87 KDM4E (0.69) SMN1; SMN2ACEALOX15KDM4EMAPT
SCHEMBL170877 0.87 KDM4E (0.69) SMN1; SMN2ACEALOX15KDM4EMAPT
SCHEMBL23872546 0.86 ACE (0.62) SMN1; SMN2ACEALOX15KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8461289-B2 Bioresorbable polymers synthesized from monomer analogs of natural metabolites RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-06-11 — — US claimed
US-8415449-B2 Bioresorbable polymers synthesized from monomer analogs of natural metabolites RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2013-04-09 — — US claimed
US-20120302719-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-11-29 — — US claimed
US-20120197001-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2012-08-02 — — US claimed
US-20110275782-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2011-11-10 — — US claimed
EP-2334712-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES Rutgers, The State University of New Jersey (US) 2011-06-22 — — EP claimed
WO-2010033640-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2010-03-25 — — WO claimed
US-20260133115-A1 MASS CYTOMETRY REAGENTS AND METHODS FOR SIGNAL AMPLIFICATION STANDARD BIOTOOLS CANADA INC. (CA) 2026-05-14 — — US disclosed
US-20260062448-A1 CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND USES THEREOF APELLIS PHARMACEUTICALS INC (US) 2026-03-05 — — US disclosed
US-12540893-B2 Mass cytometry reagents and methods for signal amplification STANDARD BIOTOOLS CANADA INC. (CA) 2026-02-03 — — US disclosed
US-12528836-B2 Dosing regimens APELLIS PHARMACEUTICALS, INC. (US) 2026-01-20 — — US disclosed
US-12458695-B2 Dosing regimens and related compositions and methods APELLIS PHARMACEUTICALS, INC. (US) 2025-11-04 — — US disclosed
EP-4634116-A1 VANADIUM COMPLEXES WITH NITROGEN AND OXYGEN DONOR ATOMS Borchers GmbH (DE) 2025-10-22 — — EP disclosed
WO-2005029066-A2 DIAGNOSTIC MARKERS AND PHARMACOLOGICAL TARGETS IN HEART FAILURE AND RELATED REAGENTS AND METHODS OF USE THEREOF AGILENT TECHNOLOGIES, INC. (US) 2005-03-31 — — WO disclosed
WO-2005021712-A2 MODIFIED MOLECULAR BEACONS GEORGIA TECH RESEARCH CORPORATION (US) 2005-03-10 — — WO disclosed
WO-2005019429-A2 COMPOSITIONS AND METHODS FOR ENHANCING PHAGOCYTOSIS OR PHAGOCYTE ACTIVITY POTENTIA PHARMACEUTICALS, INC. (US) 2005-03-03 — — WO disclosed
WO-2005014615-A2 SELF-ASSEMBLING PEPTIDES INCORPORATING MODIFICATIONS AND METHODS OF USE THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-02-17 — — WO disclosed
US-20050014181-A1 Methods and compositions for the assessment of polymer assembly NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-01-20 — — US disclosed
US-20040241748-A1 Self-assembling arrays and uses thereof POINTILLISTE, INC. 2004-12-02 — — US disclosed
WO-2004071641-A2 SELF-ASSEMBLING ARRAYS AND USES THEREOF POINTILLISTE, INC. (US) 2004-08-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12458695-B2 Dosing regimens and related compositions and methods C1QBP, C3AR1, C9 SMN1; SMN2 1241/4885ACE 191/4885ALOX15 1398/4885
US-20110275782-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES BCAT2, WASF2, THEM6 SMN1; SMN2 4292/4885ACE 2039/4885ALOX15 1612/4885
US-20120302719-A1 BIORESORBABLE POLYMERS SYNTHESIZED FROM MONOMER ANALOGS OF NATURAL METABOLITES BCAT2, WASF2, THEM6 SMN1; SMN2 4292/4885ACE 2039/4885ALOX15 1612/4885
US-12540893-B2 Mass cytometry reagents and methods for signal amplification CD47, HLCS, SRMS SMN1; SMN2 1755/4885ACE 1542/4885ALOX15 4850/4885
US-20260133115-A1 MASS CYTOMETRY REAGENTS AND METHODS FOR SIGNAL AMPLIFICATION SRMS, THOC2, TSPO SMN1; SMN2 2729/4885ACE 2199/4885ALOX15 2415/4885
US-12528836-B2 Dosing regimens CFD, CFB, VIP SMN1; SMN2 3343/4885ACE 809/4885ALOX15 2113/4885
US-20260062448-A1 CELL-REACTIVE, LONG-ACTING, OR TARGETED COMPSTATIN ANALOGS AND USES THEREOF MASP2, CLEC4M, C1QBP SMN1; SMN2 3125/4885ACE 476/4885ALOX15 1590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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