Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | ACE | P12821 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | APAF1 | O14727 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | MPO | P05164 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.64 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.64 |
| ▸ | ITGAL | P20701 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167226 | 1.00 | ALOX15 (0.68) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL30782236 | 0.90 | ALOX15 (0.70) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL170878 | 0.88 | KDM4E (0.69) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL170877 | 0.88 | KDM4E (0.69) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| Abrine (L) SCHEMBL18777 | 0.87 | ALOX15 (0.70) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| Water SCHEMBL5384989 | 0.87 | KDM4E (0.68) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL352261 | 0.87 | SMN1; SMN2 (0.69) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL1332183 | 0.87 | ALOX15 (0.67) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL20816097 | 0.87 | ALOX15 (0.67) | ALOX15ACESMN1; SMN2KDM4EMAPT | |
| SCHEMBL12583690 | 0.87 | ALOX15 (0.67) | ALOX15ACESMN1; SMN2KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350215-A1 | CYSTINE KNOT SCAFFOLD PLATFORM | H. Hoffnabb-La Roche Ag (CH) | 2018-07-25 | — | — | EP | claimed |
| WO-2017049009-A1 | CYSTINE KNOT SCAFFOLD PLATFORM | GENENTECH, INC. (US) | 2017-03-23 | — | — | WO | claimed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | claimed |
| EP-2120555-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Heller, Adam (US) | 2009-11-25 | — | — | EP | claimed |
| US-20080287866-A1 | Methods and compositions for the treatment of pain | HELLER ADAM | 2008-11-20 | — | — | US | claimed |
| WO-2008094664-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2008-08-07 | — | — | WO | claimed |
| US-3991107-A | Haloamine transfer | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1976-11-09 | — | — | US | claimed |
| US-20260071243-A1 | BIOLOGICAL PRODUCTION OF TRYPTOPHAN-DERIVED PRODUCTS | UNIV TEXAS (US) | 2026-03-12 | — | — | US | disclosed |
| EP-4110328-B1 | INTERVENTION STRATEGY FOR PREVENTION OR TREATMENT OF DIABETES MELLITUS, AUTOIMMUNE DISEASE, INFLAMMATORY DISEASE OR CARDIOVASCULAR DISEASE | Stichting Amsterdam UMC (NL) | 2026-01-07 | — | — | EP | disclosed |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | UNIV DANMARKS TEKNISKE (DK) | 2025-11-20 | — | — | US | disclosed |
| US-20250302807-A1 | INTERVENTION STRATEGY FOR PREVENTION OR TREATMENT OF DIABETES MELLITUS, AUTOIMMUNE DISEASE, INFLAMMATORY DISEASE OR CARDIOVASCULAR DISEASE | ACAD MEDISCH CT (NL) | 2025-10-02 | — | — | US | disclosed |
| EP-4552700-A2 | INTERVENTION STRATEGY FOR PREVENTION OR TREATMENT OF DIABETES MELLITUS, AUTOIMMUNE DISEASE, INFLAMMATORY DISEASE OR CARDIOVASCULAR DISEASE | Stichting Amsterdam UMC (NL) | 2025-05-14 | — | — | EP | disclosed |
| WO-2025096941-A1 | BIOSYNTHESIS OF TRYPTAMINES AND RELATED COMPOUNDS | MIAMI UNIVERSITY (US) | 2025-05-08 | — | — | WO | disclosed |
| EP-0686144-A1 | NEW COMPOUNDS | Astra Aktiebolag (SE) | 1995-12-13 | — | — | EP | disclosed |
| EP-0501378-B1 | NMDA Antagonists | MERRELL DOW PHARMA (US) | 1995-01-11 | — | — | EP | disclosed |
| WO-1994019315-A1 | NEW COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1994-09-01 | — | — | WO | disclosed |
| US-3988349-A | Salts of N-formyl-6-chlorotryptophan and α-methyl-p-nitrobenzylamine | HOFFMANN-LA ROCHE INC. (US) | 1976-10-26 | — | — | US | disclosed |
| US-3965129-A | THREO-EPOXYACONITIC ACID BIS-R(+)-ALPHA-METHYL-P-NITROBENZYLAMINE SALT | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3965121-A | Salts of the γ-lactone of (-)-threo-hydroxycitric acid with R(+)-α-methyl-p-nitrobenzylamine | HOFFMANN-LA ROCHE INC. (US) | 1976-06-22 | — | — | US | disclosed |
| US-3943628-A | Spoon excavator for applying chemically acting tooth decay attacking fluid | KRONMAN JOSEPH H | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287866-A1 | Methods and compositions for the treatment of pain | ACHE, S100P, P2RX3 | ALOX15 442/4885ACE 462/4885SMN1; SMN2 887/4885 |
| US-20260071243-A1 | BIOLOGICAL PRODUCTION OF TRYPTOPHAN-DERIVED PRODUCTS | TPH1, TPH2, SLC6A4 | ALOX15 3810/4885ACE 3596/4885SMN1; SMN2 4650/4885 |
| US-20250354108-A1 | METHODS FOR PRODUCING MONOTERPENE INDOLE ALKALOIDS | INMT, KARS1, MIA3 | ALOX15 25/4885ACE 744/4885SMN1; SMN2 4599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.