Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29426325 | 1.00 | TRHR (0.71) | TRHR | |
| SCHEMBL9571152 | 0.84 | TRHR (0.59) | TRHR | |
| Protirelin SCHEMBL10087946 | 0.83 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL10087855 | 0.83 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL33419 | 0.83 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL16091769 | 0.83 | TRHR (1.00) | TRHR | |
| Protirelin SCHEMBL4406163 | 0.80 | TRHR (0.93) | TRHR | |
| Protirelin SCHEMBL1007386 | 0.79 | TRHR (0.91) | TRHR | |
| Azetirelin SCHEMBL195158 | 0.78 | TRHR (0.85) | TRHR | |
| SCHEMBL7649430 | 0.78 | TRHR (0.57) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713935-B2 | Compounds that modulate TRH actions | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2010-05-11 | — | — | US | disclosed |
| US-20070265202-A1 | Compounds That Modulate Trh Actions | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE O (IE) | 2007-11-15 | — | — | US | disclosed |
| US-20070265202-A1 | Compounds That Modulate Trh Actions | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE O (IE) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265202-A1 | Compounds That Modulate Trh Actions | TRHR, TRHDE, TSHR | TRHR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.