Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
| ▸ | GNPAT | O15228 | 2/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.33 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22100977 | 1.00 | KISS1R (0.44) | KISS1RHTR2AHRH1CPB2FOLH1 | |
| SCHEMBL12890791 | 1.00 | KISS1R (0.44) | KISS1RHTR2AHRH1CPB2FOLH1 | |
| SCHEMBL434550 | 0.94 | CPB2 (0.43) | KISS1RHTR2AHRH1CPB2FOLH1 | |
| SCHEMBL19401625 | 0.94 | CPB2 (0.43) | KISS1RHTR2AHRH1CPB2FOLH1 | |
| SCHEMBL13057114 | 0.94 | CPB2 (0.43) | KISS1RHTR2AHRH1CPB2FOLH1 | |
| SCHEMBL14002511 | 0.86 | FOLH1 (0.35) | KISS1RHTR2AHRH1CPB2FOLH1 | |
| SCHEMBL29187495 | 0.86 | FOLH1 (0.35) | KISS1RHTR2AHRH1CPB2FOLH1 | |
| SCHEMBL1082586 | 0.84 | NOD1 (0.43) | FOLH1NOD1GNPATNAALAD2RIMKLA | |
| SCHEMBL13366903 | 0.83 | KISS1R (0.53) | KISS1RHTR2AHRH1CPB2FOLH1 | |
| SCHEMBL14525182 | 0.83 | KISS1R (0.53) | KISS1RHTR2AHRH1CPB2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718802-B2 | Agonist or antgonist and binders and inversion of agonist; use in the treatment of metabolic, immune, infection-related and melanocortin receptor mediated disorders | PALATIN TECHNOLOGIES, INC. (US) | 2010-05-18 | — | — | US | disclosed |