SCHEMBL434550

SCHEMBL434550

CNCCCC[C@H](NC)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 1/20 0.43
FOLH1 Q04609 10/20 0.42
KISS1R Q969F8 1/20 0.39
KDM4A O75164 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
NOD1 Q9Y239 1/20 0.35
EPHX1 P07099 1/20 0.34
HTR2A P28223 1/20 0.34
HRH1 P35367 1/20 0.34
ALB P02768 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19401625 1.00 CPB2 (0.43) CPB2FOLH1KISS1RKDM4AKDM4C
SCHEMBL13057114 1.00 CPB2 (0.43) CPB2FOLH1KISS1RKDM4AKDM4C
SCHEMBL22100977 0.94 KISS1R (0.44) CPB2FOLH1KISS1RKDM4AKDM4C
SCHEMBL13323375 0.94 KISS1R (0.44) CPB2FOLH1KISS1RKDM4AKDM4C
SCHEMBL12890791 0.94 KISS1R (0.44) CPB2FOLH1KISS1RKDM4AKDM4C
SCHEMBL3438650 0.86 CPB2 (0.42) CPB2FOLH1KISS1RKDM4AKDM4C
SCHEMBL15393668 0.86 FOLH1 (0.43) CPB2FOLH1KISS1RSMN1; SMN2NOD1
SCHEMBL29187495 0.85 FOLH1 (0.35) CPB2FOLH1KISS1RSMN1; SMN2HTR2A
SCHEMBL14002511 0.85 FOLH1 (0.35) CPB2FOLH1KISS1RSMN1; SMN2HTR2A
SCHEMBL25476072 0.84 FOLH1 (0.41) FOLH1SMN1; SMN2NOD1ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 212 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2024-12-05 US claimed
US-20110064668-A1 J-SUPERFAMILY CONOTOXIN PEPTIDES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2011-03-17 US claimed
US-20100093620-A1 TYROSINE-RICH CONOPEPTIDES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2010-04-15 US claimed
WO-2007145987-A1 J-SUPERFAMILY CONOTOXIN PEPTIDES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2007-12-21 WO claimed
US-20060205656-A1 P-superfamily conopeptides COGNETIX, INC. (US) 2006-09-14 US claimed
US-20050143560-A1 Polypeptide analgesics from snail venom; analogous to the naturally available peptides, and which preferably include two disulfide bonds UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2005-06-30 US claimed
US-20050096270-A1 I-superfamily conotoxins UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2005-05-05 US claimed
US-20040259794-A1 MuO-conopeptides and their use as local anesthetics COGNETIX, INC. (US) 2004-12-23 US claimed
EP-1307215-A4 I-SUPERFAMILY CONOTOXINS UNIV UTAH RES FOUND (US) 2004-09-08 EP claimed
EP-1185286-A4 MU O-CONOPEPTIDES AND THEIR USE AS LOCAL ANESTHETICS UNIV UTAH RES FOUND (US) 2004-09-08 EP claimed
US-6767896-B1 POLYPEPTIDE ANALGESICS FROM SNAIL VENOM COGNETIX, INC. 2004-07-27 US claimed
US-6767895-B2 PEPTIDE FOR USE IN THE TREATMENT OF PAIN, STROKE, NERVOUS SYSTEM DISORDERS, MULTIPLE SCLEROSIS, HUNTINGTON'S CHOREA, FOOD POISONING, CARDIOVASCULAR DISORDERS, DRUG ADDICTION, MUSCULAR DISORDERS, EPILEPSY COGNETIX, INC. 2004-07-27 US claimed
US-20030166560-A1 Snail/mollusc polypeptides; anticonvulsant drug screening HOOPER DAVID (US) 2003-09-04 US claimed
EP-1307215-A2 I-SUPERFAMILY CONOTOXINS The University of Utah Research Foundation (US) 2003-05-07 EP claimed
US-20020198145-A1 MuO-conopeptides and their use as local anesthetics COGNETIX, INC. (US) 2002-12-26 US claimed
US-20020102607-A1 I-superfamily conotoxins UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2002-08-01 US claimed
EP-1185286-A1 MU O-CONOPEPTIDES AND THEIR USE AS LOCAL ANESTHETICS The University of Utah Research Foundation (US) 2002-03-13 EP claimed
WO-2002002590-A2 I-SUPERFAMILY CONOTOXINS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2002-01-10 WO claimed
WO-2001035985-A1 P-SUPERFAMILY CONOPEPTIDES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2001-05-25 WO claimed
WO-2000076532-A1 νO-CONOPEPTIDES AND THEIR USE AS LOCAL ANESTHETICS UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2000-12-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110064668-A1 J-SUPERFAMILY CONOTOXIN PEPTIDES KCNQ1, KCNQ2, KCNA3 CPB2 2492/4885FOLH1 2259/4885KISS1R 80/4885
US-20240400499-A1 NOVEL AMINO ACID DERIVATIVES BCAT1, BCAT2, PELP1 CPB2 1133/4885FOLH1 1381/4885KISS1R 4361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.