Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3130161 | 0.98 | MAPT (0.41) | MAPTCYP3A4ALDH1A1TDP1MAPK1 | |
| SCHEMBL8641903 | 0.89 | MAPT (0.47) | MAPTCYP3A4ALDH1A1TDP1MAPK1 | |
| SCHEMBL707809 | 0.85 | MAPT (0.55) | MAPTCYP3A4ALDH1A1TDP1MAPK1 | |
| SCHEMBL2440814 | 0.84 | ALDH1A1 (0.53) | MAPTCYP3A4ALDH1A1TDP1MAPK1 | |
| SCHEMBL3885331 | 0.83 | ALDH1A1 (0.52) | MAPTCYP3A4ALDH1A1TDP1MAPK1 | |
| SCHEMBL295156 | 0.83 | ALDH1A1 (0.52) | MAPTCYP3A4ALDH1A1TDP1MAPK1 | |
| SCHEMBL8678729 | 0.83 | ALDH1A1 (0.52) | MAPTCYP3A4ALDH1A1TDP1MAPK1 | |
| SCHEMBL294907 | 0.83 | ALDH1A1 (0.52) | MAPTCYP3A4ALDH1A1TDP1MAPK1 | |
| SCHEMBL2444795 | 0.79 | ALDH1A1 (0.55) | MAPTCYP3A4ALDH1A1TDP1MAPK1 | |
| Aniline SCHEMBL28090769 | 0.77 | KCNH2 (0.47) | MAPTCYP3A4ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053902-A2 | TRYPTASE ENZYME INHIBITING AMINOTHIOPHENOLS | HERBALSCIENCE GROUP, LLC (US) | 2010-05-14 | — | — | WO | disclosed |
| US-20100113608-A1 | Tryptase Enzyme Inhibiting Aminothiophenols | HERBALSCIENCE GROUP, LLC | 2010-05-06 | — | — | US | disclosed |
| US-20100113608-A1 | Tryptase Enzyme Inhibiting Aminothiophenols | HERBALSCIENCE GROUP, LLC | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113608-A1 | Tryptase Enzyme Inhibiting Aminothiophenols | TPSG1, TPSB2, TPSAB1 | MAPT 940/4885CYP3A4 812/4885ALDH1A1 2039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.