Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.57 |
| ▸ | CTSL | P07711 | 2/20 | 0.57 |
| ▸ | CTSS | P25774 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 3/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP4 | P49662 | 1/20 | 0.52 |
| ▸ | CASP5 | P51878 | 1/20 | 0.52 |
| ▸ | CASP9 | P55211 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13323998 | 0.88 | CTSB (0.59) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL6669609 | 0.88 | CTSB (0.63) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL13323958 | 0.87 | CTSK (0.51) | CTSBCTSLCTSSPSMB5CTSK | |
| SCHEMBL13324018 | 0.85 | CASP3 (0.56) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL13323970 | 0.84 | MME (0.55) | CTSLCTSSCASP3CASP1CASP9 | |
| SCHEMBL13323941 | 0.84 | ACE (0.56) | CTSBCTSLCTSSCTSKMME | |
| SCHEMBL13323971 | 0.84 | MME (0.48) | CTSBCTSLCTSSCTSKMME | |
| SCHEMBL13323973 | 0.83 | SIRT2 (0.59) | CTSLCTSSMMEECE1 | |
| SCHEMBL6666188 | 0.83 | CTSB (0.57) | CTSBCTSLCTSSMEN1KMT2A | |
| SCHEMBL13323943 | 0.82 | MME (0.56) | CTSLCASP3CASP1CASP4CASP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723307-B2 | Amino acid derivatives and pharmaceutical uses thereof | ASTON UNIVERSITY (GB) | 2010-05-25 | — | — | US | disclosed |
| US-20080200511-A1 | Novel Compounds and Methods of Using the Same | ASTON UNIVERSITY (GB) | 2008-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080200511-A1 | Novel Compounds and Methods of Using the Same | F3, IL4I1, TPMT | CTSB 1003/4885CTSL 2160/4885CTSS 1071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.