Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531097 | 0.89 | CYP1A2 (0.48) | CYP1A2CYP3A4CYP2C19KMT2AHPGD | |
| SCHEMBL13326046 | 0.86 | PTGS2 (0.35) | AGBL2PTGS2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13303524 | 0.84 | GAA (0.39) | PTGS2CYP1A2CYP3A4CYP2C19KMT2A | |
| SCHEMBL13326422 | 0.83 | DHODH (0.38) | AGBL2PTGS2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1531177 | 0.76 | GABRB3 (0.38) | CYP1A2CYP3A4CYP2C19DHODHIKBKB | |
| SCHEMBL13325363 | 0.76 | DRD1 (0.31) | — | |
| SCHEMBL13325368 | 0.75 | DHODH (0.38) | AGBL2PTGS2CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL13303527 | 0.74 | ALDH1A1 (0.44) | CYP1A2CYP2C19KMT2ALMNAALDH1A1 | |
| SCHEMBL1531085 | 0.72 | CYP1A2 (0.52) | CYP1A2CYP3A4CYP2C19KMT2AHPGD | |
| SCHEMBL18312359 | 0.72 | NPSR1 (0.47) | AGBL2PTGS2CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152443-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152443-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | CYP51A1, CYP4F11, WEE1 | AGBL2 2404/4885PTGS2 1707/4885CYP1A2 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.