Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRB3 | P28472 | 7/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1531097 | 0.84 | CYP1A2 (0.48) | L3MBTL1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1531184 | 0.83 | IKBKB (0.39) | GABRB3GABRA2GABRB2IKBKBDHODH | |
| SCHEMBL13325971 | 0.76 | AGBL2 (0.36) | IKBKBDHODHL3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL1531076 | 0.73 | DHODH (0.39) | GABRB3GABRA2GABRB2IKBKBDHODH | |
| SCHEMBL1531388 | 0.73 | GABRB3 (0.36) | GABRB3GABRA2GABRB2CYP1A2CYP2C19 | |
| SCHEMBL13406009 | 0.72 | DHODH (0.36) | IKBKBP2RX7DHODHL3MBTL1CYP1A2 | |
| SCHEMBL13326046 | 0.71 | PTGS2 (0.35) | DHODHL3MBTL1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL20528672 | 0.70 | GABRB3 (0.39) | GABRB3GABRA2GABRB2L3MBTL1 | |
| SCHEMBL1531212 | 0.70 | ALDH1A1 (0.43) | L3MBTL1 | |
| SCHEMBL13303524 | 0.69 | GAA (0.39) | CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362852-B1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | SAGAMI CHEM RES (JP) | 2011-04-06 | — | — | EP | disclosed |
| EP-2292606-A1 | Pyrazole derivative, its intermediate, and herbicide containing the same as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2011-03-09 | — | — | EP | disclosed |
| US-20100152443-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2010-06-17 | — | — | US | disclosed |
| US-7700786-B2 | Pyrazole derivative, intermediate therefor, processes for producing these, and herbicide containing these as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2010-04-20 | — | — | US | disclosed |
| US-20050070441-A1 | Pyrazole derivative, intermediate therefor, processes for producing these, and herbicide containing these as active ingredient | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 2005-03-31 | — | — | US | disclosed |
| EP-1362852-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 2003-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152443-A1 | PYRAZOLE DERIVATIVE, INTERMEDIATE THEREFOR, PROCESSES FOR PRODUCING THESE, AND HERBICIDE CONTAINING THESE AS ACTIVE INGREDIENT | CYP51A1, CYP4F11, WEE1 | GABRB3 1745/4885GABRA2 2297/4885GABRB2 1550/4885 |
| US-20050070441-A1 | Pyrazole derivative, intermediate therefor, processes for producing these, and herbicide containing these as active ingredient | CYP51A1, CYP4F11, WEE1 | GABRB3 1745/4885GABRA2 2297/4885GABRB2 1550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.