Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.64 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | SYK | P43405 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13326017 | 1.00 | NFKB1 (0.64) | NFKB1KCNH3MAPTSMN1; SMN2APP | |
| SCHEMBL28736378 | 0.91 | LMNA (0.63) | NFKB1KCNH3MAPTSMN1; SMN2APP | |
| SCHEMBL4544828 | 0.86 | EGFR (0.68) | KCNH3MAPTSMN1; SMN2APPPOLB | |
| SCHEMBL4544834 | 0.83 | KCNH3 (0.70) | KCNH3MAPTPOLBNPC1RAB9A | |
| SCHEMBL4544861 | 0.83 | KCNH3 (0.70) | KCNH3MAPTPOLBNPC1RAB9A | |
| SCHEMBL20820089 | 0.82 | NFKB1 (0.76) | NFKB1MAPTAPPPOLBNPC1 | |
| SCHEMBL13326014 | 0.82 | GALR2 (0.67) | KCNH3MAPTSMN1; SMN2APPRAB9A | |
| SCHEMBL4544829 | 0.82 | KCNH3 (0.68) | KCNH3MAPTSMN1; SMN2APPPOLB | |
| SCHEMBL28736393 | 0.82 | KCNH3 (0.68) | KCNH3MAPTAPPPOLBNPC1 | |
| SCHEMBL4544833 | 0.81 | KCNH3 (0.59) | KCNH3MAPTSMN1; SMN2APPPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108191774-B | Heterocyclic compound, preparation method and application thereof | 中国药科大学 | 2022-05-24 | — | — | CN | disclosed |