Tetrahydrocortisone

Tetrahydrocortisone

SCHEMBL1332665

CC12CC[C@@H](O)CC1CCC1C2C(=O)CC2(C)C1CC[C@]2(O)C(=O)CO

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 4/20 0.79
CYP3A4 P08684 4/20 0.77
GABRA1 P14867 5/20 0.58
GABRB2 P47870 5/20 0.58
GABRG2 P18507 3/20 0.58
GABRB3 P28472 3/20 0.58
GABRA2 P47869 3/20 0.58
CYP2C9 P11712 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
GLA P06280 1/20 0.58
HSD17B10 Q99714 6/20 0.54
LMNA P02545 2/20 0.54
ALDH1A1 P00352 2/20 0.54
NR3C1 P04150 2/20 0.54
SERPINA6 P08185 2/20 0.54
CYP2D6 P10635 1/20 0.54
TSHR P16473 1/20 0.54
SHBG P04278 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrocortisone SCHEMBL4111245 1.00 G6PD (0.79) G6PDCYP3A4GABRA1GABRB2GABRG2
Tetrahydrocortisone SCHEMBL1184193 1.00 G6PD (0.79) G6PDCYP3A4GABRA1GABRB2GABRG2
Tetrahydrocortisone SCHEMBL5610354 1.00 G6PD (0.79) G6PDCYP3A4GABRA1GABRB2GABRG2
Tetrahydrocortisone SCHEMBL1184192 1.00 G6PD (0.79) G6PDCYP3A4GABRA1GABRB2GABRG2
Tetrahydrocortisone SCHEMBL193711 1.00 G6PD (0.79) G6PDCYP3A4GABRA1GABRB2GABRG2
Tetrahydrocortisone SCHEMBL5139991 0.99 G6PD (0.77) G6PDCYP3A4GABRA1GABRB2GABRG2
Tetrahydrocortisone SCHEMBL8366487 0.99 G6PD (0.77) G6PDCYP3A4GABRA1GABRB2GABRG2
Tetrahydrocortisone SCHEMBL8360187 0.99 G6PD (0.77) G6PDCYP3A4GABRA1GABRB2GABRG2
Tetrahydrocortisone SCHEMBL11169159 0.99 G6PD (0.77) G6PDCYP3A4GABRA1GABRB2GABRG2
Tetrahydrocortisone SCHEMBL6461669 0.99 G6PD (0.77) G6PDCYP3A4GABRA1GABRB2GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577526-B2 Massively parallel on-chip construction of synthetic microbial communities THE BROAD INSTITUTE, INC. (US) 2026-03-17 US disclosed
US-20250376656-A1 MASSIVELY PARALLEL ON-CHIP CONSTRUCTION OF SYNTHETIC MICROBIAL COMMUNITIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2025-12-11 US disclosed
WO-2025068686-A1 TREATMENT FOR BATTEN DISEASE THE ROYAL VETERINARY COLLEGE (GB) 2025-04-03 WO disclosed
US-20220228190-A1 MASSIVELY PARALLEL ON-CHIP CONSTRUCTION OF SYNTHETIC MICROBIAL COMMUNITIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2022-07-21 US disclosed
US-9673030-B2 Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry EMORY UNIVERSITY (US) 2017-06-06 US disclosed
CN-102731499-B Lactam compound and the application as medicine thereof Because of C1-esteraseremmer-N parent corporation (US) 2016-01-13 CN disclosed
CN-104672311-A Lipopeptides for delivery of nucleic acids MARINA BIOTECH INC 2015-06-03 CN disclosed
US-20140309186-A1 Metabolomics-Based Identification of Disease-Causing Agents GEORGIA TECH RESEARCH CORPORATION 2014-10-16 US disclosed
CN-102124102-B Methods for optimizing electroporation MAXCYTE INC 2013-12-18 CN disclosed
CN-101412742-B Nitric acid ester medicament for inhibiting angiogenesis TIANJIN JINYAO GROUP CO LTD 2013-07-31 CN disclosed
CN-101156860-A Use of mometasone furoate for treating airway passage and lung diseases SCHERING CORP (US) 2008-04-09 CN disclosed
CN-101103016-A Inhibitors of 11-beta hydroxyl steroid dehydrogenase type I and methods of using the same INCYTE CORP (US) 2008-01-09 CN disclosed
CN-100358528-C Use of mometasone furoate for preparing medicine SCHERING CORP (US) 2008-01-02 CN disclosed
CN-101098856-A Lactam compounds and their use as pharmaceuticals INCYTE SAN DIEGO INC (US) 2008-01-02 CN disclosed
CN-101001850-A Amido compounds and their use as pharmaceuticals INCYTE CORP (US) 2007-07-18 CN disclosed
CN-1531967-A Use of mometasone furoate for treating airway nassage and lung diseases ���鹫˾ 2004-09-29 CN disclosed
CN-1342146-A Substituted 1-oxo-and 1, 3-dioxoisoindolines and their use in pharmaceutical compositions for reducing inflammatory cytokine levels CELGENE CORP (US) 2002-03-27 CN disclosed
US-6274118-B1 INJECTING PATIENT HAVING ENDOCRINE CANCER IN NON-PROSTATIC TISSUE WITH BIOLOGICAL BINDING UNITS WHICH BIND TO PROSTATE SPECIFIC ANTIGEN PRODUCED BY NON-PROSTATIC TISSUE NORDION INTERNATIONAL INC. (CA) 2001-08-14 US disclosed
CN-1139384-A Use of mometasone furoate for treating respiratory and pulmonary diseases SCHERING CORP (US) 1997-01-01 CN disclosed
WO-1995002424-A1 LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN NORDION INTERNATIONAL INC. (CA) 1995-01-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577526-B2 Massively parallel on-chip construction of synthetic microbial communities STUB1, SAMM50, CD14 G6PD 3668/4885CYP3A4 1640/4885GABRA1 3693/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.