SCHEMBL1332671

SCHEMBL1332671

CC(=O)C(=O)Oc1c[nH]c2ccc(O)cc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 1/20 0.49
NPSR1 Q6W5P4 5/20 0.47
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 4/20 0.47
BLM P54132 3/20 0.47
SPR P35270 3/20 0.47
HPGD P15428 2/20 0.47
CYP3A4 P08684 2/20 0.47
MAPT P10636 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 2/20 0.47
IDO1 P14902 1/20 0.47
NOTUM Q6P988 1/20 0.47
NFKB1 P19838 3/20 0.47
LMNA P02545 3/20 0.47
TSHR P16473 2/20 0.47
PMP22 Q01453 2/20 0.47
CYP2C9 P11712 2/20 0.47
GLA P06280 1/20 0.47
HTR2C P28335 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19846981 0.88 SLC22A6 (0.64) SLC22A6NPSR1ALDH1A1KDM4EBLM
SCHEMBL28918308 0.81 HTR1A (0.50) SLC22A6NPSR1ALDH1A1KDM4EBLM
SCHEMBL28034308 0.81 NPSR1 (0.50) SLC22A6NPSR1ALDH1A1KDM4EBLM
SCHEMBL125250 0.80 SLC22A6 (0.76) SLC22A6ALDH1A1KDM4EBLMHPGD
SCHEMBL4626534 0.76 NR4A2 (0.52) SLC22A6ALDH1A1KDM4EHPGDMAPT
SCHEMBL21809188 0.76 PBRM1 (0.61) NPSR1ALDH1A1KDM4EBLMSPR
SCHEMBL9012528 0.75 NR4A2 (0.54) SLC22A6ALDH1A1SPRIDO1HTR2A
SCHEMBL9117858 0.72 SLC22A6 (0.64) SLC22A6ALDH1A1KDM4EHPGDLMNA
SCHEMBL7725553 0.71 SLC22A6 (0.62) SLC22A6KDM4EIDO1HTR2AHSD17B10
SCHEMBL14575156 0.71 SLC22A6 (0.62) SLC22A6ALDH1A1KDM4EHPGDIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9673030-B2 Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry EMORY UNIVERSITY (US) 2017-06-06 US disclosed
US-20110282587-A1 COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY EMORY UNIVERSITY (US) 2011-11-17 US disclosed