Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27920538 | 0.88 | SLC22A6 (0.64) | NR4A2HSD17B10KDM4ESLC22A6KIF11 | |
| SCHEMBL9012528 | 0.84 | NR4A2 (0.54) | NR4A2HSD17B10SLC22A6HTR2AALDH1A1 | |
| SCHEMBL125250 | 0.80 | SLC22A6 (0.76) | NR4A2KDM4ESLC22A6L3MBTL1LMNA | |
| SCHEMBL1332671 | 0.76 | SLC22A6 (0.49) | HSD17B10KDM4ESLC22A6HTR2ALMNA | |
| SCHEMBL17032685 | 0.76 | NR4A2 (0.69) | NR4A2HSD17B10KDM4EKIF11L3MBTL1 | |
| SCHEMBL8269419 | 0.75 | NR4A2 (0.54) | NR4A2HSD17B10KDM4EKIF11HTR2A | |
| SCHEMBL9117858 | 0.75 | SLC22A6 (0.64) | NR4A2HSD17B10KDM4ESLC22A6L3MBTL1 | |
| SCHEMBL27614790 | 0.73 | NR4A2 (0.49) | NR4A2HSD17B10KDM4ESLC22A6KIF11 | |
| SCHEMBL8915869 | 0.71 | HTR1B (0.44) | HSD17B10KDM4ESLC22A6LMNAHTR2C | |
| SCHEMBL5530414 | 0.71 | SLC22A6 (0.62) | NR4A2SLC22A6MTNR1AMTNR1BIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529776-B1 | Amino acid derivatives and sweetening agent | AJINOMOTO KK (JP) | 2008-03-05 | — | — | EP | disclosed |
| US-7244462-B2 | Amino acid derivative and sweetening agent | AJINOMOTO CO., INC. (JP) | 2007-07-17 | — | — | US | disclosed |
| US-20050118317-A1 | Novel amino acid derivative and sweetening agent | AJINOMOTO CO., INC. (JP) | 2005-06-02 | — | — | US | disclosed |
| EP-1529776-A2 | Amino acid derivatives and sweetening agent | Ajinomoto Co., Inc. (JP) | 2005-05-11 | — | — | EP | disclosed |