Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13359911 | 0.93 | PTGS2 (0.41) | PTGS2CA12CA1CA9VDR | |
| SCHEMBL241884 | 0.82 | CA1 (0.52) | CA12CA1CA9VDRCYP2D6 | |
| SCHEMBL3975042 | 0.81 | L3MBTL1 (0.49) | CA12CA1CA9CYP2D6ALDH1A1 | |
| SCHEMBL22497343 | 0.81 | ALDH1A1 (0.45) | CA12CA1CA9VDRCYP2D6 | |
| SCHEMBL1581431 | 0.80 | PTGS2 (0.62) | PTGS2VDRCYP24A1GAAALDH1A1 | |
| SCHEMBL19733679 | 0.79 | MBTD1 (0.55) | MEN1RAB9AKMT2APKM | |
| SCHEMBL30225654 | 0.78 | HPGD (0.60) | CA1CA9VDRMMP2ALDH1A1 | |
| SCHEMBL3694647 | 0.78 | HPGD (0.60) | CA1CA9VDRMMP2ALDH1A1 | |
| SCHEMBL890725 | 0.78 | ALDH1A1 (0.50) | CA12CA1CA9VDRCYP2D6 | |
| Water SCHEMBL7788572 | 0.78 | CA1 (0.50) | CA12CA1CA9VDRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723322-B2 | Fluoride carrier for positron emission tomography | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-25 | — | — | US | disclosed |
| US-20070232521-A1 | Fluoride carrier for positron emission tomography | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-04 | — | — | US | disclosed |
| US-20070232521-A1 | Fluoride carrier for positron emission tomography | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232521-A1 | Fluoride carrier for positron emission tomography | AFF1, SLC67A1, SLC1A5 | PTGS2 4755/4885CA12 938/4885CA1 691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.