Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13327368 | 0.88 | KCNMA1 (0.42) | KCNMA1KMT2ARAB9ASMN1; SMN2HTT | |
| SCHEMBL8964804 | 0.74 | MAPT (0.51) | KMT2AMEN1GAARAB9ANPC1 | |
| SCHEMBL3291016 | 0.72 | KCNMA1 (0.53) | KCNMA1KMT2AMEN1GAARAB9A | |
| SCHEMBL17084351 | 0.70 | ALDH1A1 (0.42) | PDK2APEX1HTTALDH1A1 | |
| SCHEMBL17084359 | 0.69 | PDK2 (0.56) | PDK2APEX1RAB9ANPC1MAPT | |
| SCHEMBL3291279 | 0.69 | APEX1 (0.41) | KMT2AMEN1PDK2GAAAPEX1 | |
| SCHEMBL18682531 | 0.67 | APEX1 (0.43) | PDK2APEX1 | |
| SCHEMBL18838855 | 0.67 | APEX1 (0.38) | KMT2APDK2APEX1SMN1; SMN2 | |
| SCHEMBL21025425 | 0.67 | PDK2 (0.56) | PDK2APEX1RAB9ACYP2C9TDP1 | |
| SCHEMBL8964786 | 0.66 | APEX1 (0.39) | KMT2AMEN1GAAAPEX1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713452-B2 | Compounds that absorb ultraviolet light, methods of their preparation and optical lenses containing them | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-05-11 | — | — | US | disclosed |