Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11943329 | 0.95 | ALDH1A1 (0.46) | ALDH1A1KDM4ENPBWR1MCHR1DRD4 | |
| SCHEMBL11943361 | 0.91 | NPBWR1 (0.47) | ALDH1A1KDM4ENPBWR1MCHR1MAPT | |
| SCHEMBL11943401 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EDRD4DRD2MAPT | |
| SCHEMBL11943396 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPBWR1MCHR1DRD4 | |
| SCHEMBL11943430 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPBWR1MCHR1DRD2 | |
| SCHEMBL13329739 | 0.85 | KMT2A (0.41) | ALDH1A1NPBWR1MCHR1DRD4DRD2 | |
| SCHEMBL14081678 | 0.84 | NPBWR1 (0.47) | ALDH1A1NPBWR1MCHR1DRD4DRD2 | |
| SCHEMBL14080924 | 0.84 | NPBWR1 (0.44) | ALDH1A1NPBWR1MCHR1DRD4DRD2 | |
| SCHEMBL14080964 | 0.83 | NPBWR1 (0.43) | ALDH1A1NPBWR1MCHR1DRD4DRD2 | |
| SCHEMBL11943438 | 0.83 | KDM4E (0.46) | ALDH1A1KDM4EDRD4DRD2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | DPM1, GMPS, MAN2A1 | ALDH1A1 2003/4885KDM4E 1706/4885NPBWR1 3390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.