Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080924 | 0.91 | NPBWR1 (0.44) | NPBWR1MCHR1ALDH1A1TP53LMNA | |
| SCHEMBL14081679 | 0.89 | NPBWR1 (0.43) | NPBWR1MCHR1ALDH1A1TP53LMNA | |
| SCHEMBL14080964 | 0.87 | NPBWR1 (0.43) | NPBWR1MCHR1ALDH1A1TP53LMNA | |
| SCHEMBL11943329 | 0.86 | ALDH1A1 (0.46) | NPBWR1MCHR1ALDH1A1TP53LMNA | |
| SCHEMBL14080954 | 0.86 | ALDH1A1 (0.51) | NPBWR1MCHR1ALDH1A1TP53LMNA | |
| SCHEMBL14081493 | 0.85 | NPBWR1 (0.44) | NPBWR1MCHR1ALDH1A1TP53LMNA | |
| SCHEMBL14081537 | 0.85 | SMO (0.47) | NPBWR1MCHR1ALDH1A1TP53LMNA | |
| SCHEMBL13329089 | 0.84 | ALDH1A1 (0.43) | NPBWR1MCHR1ALDH1A1LMNAMEN1 | |
| SCHEMBL11943409 | 0.83 | SMO (0.45) | NPBWR1MCHR1ALDH1A1LMNAMAPK1 | |
| SCHEMBL11943361 | 0.83 | NPBWR1 (0.47) | NPBWR1MCHR1ALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115381-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2008-09-25 | — | — | WO | disclosed |