Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 7/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD3 | P35462 | 6/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11943455 | 0.94 | KMT2A (0.43) | KMT2ADRD4DRD2DRD3HTR1A | |
| SCHEMBL11943404 | 0.91 | SMO (0.43) | DRD4DRD2DRD3HTR1ANPBWR1 | |
| SCHEMBL11943440 | 0.87 | KMT2A (0.44) | KMT2ADRD4DRD2DRD3HTR1A | |
| SCHEMBL13329089 | 0.85 | ALDH1A1 (0.43) | KMT2ADRD4DRD2DRD3NPBWR1 | |
| SCHEMBL11943405 | 0.83 | DRD2 (0.40) | KMT2ADRD4DRD2DRD3HTR1A | |
| SCHEMBL11943448 | 0.82 | DRD2 (0.44) | KMT2ADRD4DRD2DRD3HTR1A | |
| SCHEMBL11943430 | 0.80 | ALDH1A1 (0.45) | DRD2DRD3NPBWR1MCHR1ALDH1A1 | |
| SCHEMBL14081678 | 0.80 | NPBWR1 (0.47) | KMT2ADRD4DRD2DRD3NPBWR1 | |
| SCHEMBL14080964 | 0.79 | NPBWR1 (0.43) | KMT2ADRD4DRD2DRD3NPBWR1 | |
| SCHEMBL11943329 | 0.79 | ALDH1A1 (0.46) | KMT2ADRD4DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100158992-A1 | PIPERAZINE-SUBSTITUTED PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | DPM1, GMPS, MAN2A1 | KMT2A 2126/4885DRD4 4876/4885DRD2 4866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.