Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329980 | 0.92 | DNM2 (0.56) | DNM2ALDH1A1LMNATP53TSHR | |
| SCHEMBL13329999 | 0.81 | ALDH1A1 (0.52) | DNM2ALDH1A1LMNATP53TSHR | |
| SCHEMBL13329996 | 0.80 | DNM2 (0.45) | DNM2ALDH1A1LMNATP53TSHR | |
| SCHEMBL13329988 | 0.79 | LMNA (0.59) | DNM2ALDH1A1LMNATP53TSHR | |
| SCHEMBL13329994 | 0.79 | DNM2 (0.44) | DNM2ALDH1A1LMNATP53TSHR | |
| SCHEMBL13329946 | 0.76 | DNM2 (0.81) | DNM2ALDH1A1LMNATP53TSHR | |
| SCHEMBL13329945 | 0.76 | DNM2 (0.81) | DNM2ALDH1A1LMNATP53TSHR | |
| SCHEMBL1194281 | 0.74 | DNM2 (0.78) | DNM2ALDH1A1LMNATP53TSHR | |
| SCHEMBL13329951 | 0.74 | DNM2 (0.77) | DNM2ALDH1A1LMNATP53TSHR | |
| SCHEMBL16608857 | 0.73 | ALDH1A1 (0.73) | DNM2ALDH1A1LMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |
| US-7722893-B2 | Use of substitute 2,4-bis (alkylamino) pyrimidines or quinzolines as antimicrobials | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2010-05-25 | — | — | US | disclosed |