Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831312 | 0.88 | CHRM2 (0.57) | KMT2AMEN1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL490337 | 0.82 | CYP4F2 (0.57) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL6366424 | 0.79 | LMNA (0.54) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL9831248 | 0.79 | GAA (0.48) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL13330463 | 0.79 | ALDH1A1 (0.63) | ALDH1A1KMT2AMEN1KDM4EHTR2A | |
| SCHEMBL9831585 | 0.78 | CHRM2 (0.53) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL30753435 | 0.78 | LMNA (0.48) | ALDH1A1KMT2AMEN1KDM4EATM | |
| SCHEMBL21715380 | 0.78 | LMNA (0.48) | ALDH1A1KMT2AMEN1KDM4EATM | |
| SCHEMBL9832305 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1KDM4ELMNA | |
| SCHEMBL9832165 | 0.77 | HTR2A (0.51) | ALDH1A1KMT2AMEN1KDM4EHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042279-B1 | SUBSTITUTED BETA-ALANINES | AVENTIS PHARMA LTD (GB) | 2005-03-02 | — | — | EP | disclosed |
| CN-1163477-C | Substituted beta-alanines | — | 2004-08-25 | — | — | CN | disclosed |
| US-6352977-B1 | ALANINE WITH PRODRUGS | AVENTIS PHARMA LIMITED (GB) | 2002-03-05 | — | — | US | disclosed |
| CN-1283181-A | Substituted beta-alanines | AWONGTISFAMA CO LTD (GB) | 2001-02-07 | — | — | CN | disclosed |
| EP-1042279-A1 | SUBSTITUTED BETA-ALANINES | Aventis Pharma Limited (GB) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999033789-A1 | SUBSTITUTED β-ALANINES | AVENTIS PHARMA LIMITED (GB) | 1999-07-08 | — | — | WO | disclosed |