SCHEMBL1333069

SCHEMBL1333069

C=C(C)C(=O)OCc1ccc(C=CC(=O)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.49
CA7 P43166 4/20 0.49
CA9 Q16790 4/20 0.49
CA14 Q9ULX7 4/20 0.49
CA4 P22748 3/20 0.49
CA6 P23280 3/20 0.49
CA5A P35218 3/20 0.49
CA5B Q9Y2D0 3/20 0.49
AKR1B10 O60218 3/20 0.49
AKR1B1 P15121 3/20 0.49
HCAR2 Q8TDS4 3/20 0.49
CA1 P00915 3/20 0.49
PKM P14618 2/20 0.49
CA2 P00918 2/20 0.49
ESR1 P03372 1/20 0.49
CA3 P07451 1/20 0.49
TYR P14679 1/20 0.49
DPP4 P27487 1/20 0.49
ESR2 Q92731 1/20 0.49
LMNA P02545 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Maleic Acid SCHEMBL28794400 0.83 HCAR2 (0.63) CA12CA7CA9CA14CA4
Coumaric Acid SCHEMBL5145297 0.83 CA12 (0.60) CA12CA7CA9CA14CA4
Juarezic Acid SCHEMBL4085006 0.82 LMNA (0.52) CA12CA7CA9CA14CA4
SCHEMBL254038 0.82 ALDH1A1 (0.50) THRBMAPK1ALDH1A1
SCHEMBL711361 0.81 ALDH1A1 (0.41) CA12CA7CA9CA14CA4
SCHEMBL12691889 0.81 CA12 (0.48) CA12CA7CA9CA14CA4
SCHEMBL3437326 0.81 CA12 (0.45) CA12CA7CA9CA14CA4
SCHEMBL12171645 0.80 THRB (0.53) CA12CA7CA9CA14CA4
SCHEMBL1333067 0.79 HCAR2 (0.49) CA12CA7CA9CA14CA4
Crotonic Acid SCHEMBL28794401 0.79 HCAR2 (0.54) CA12CA7CA9CA14CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8753686-B2 Surface-treating agents, surface-treated powders, and cosmetics comprising the same SHISEIDO CO., LTD. (JP) 2014-06-17 US disclosed
US-20110280946-A1 Surface-Treating Agents, Surface-Treated Powders, And Cosmetics Comprising The Same SHISEIDO CO., LTD. (JP) 2011-11-17 US disclosed
EP-2112179-B1 Surface-treated powders, and cosmetics comprising the same SHISEIDO CO LTD (JP) 2011-04-27 EP disclosed
EP-1803750-B1 USE OF A POLYMER FOR SURFACE-TREATING A POWDER SHISEIDO CO LTD (JP) 2009-12-09 EP disclosed
EP-2112179-A1 Surface-treated powders, and cosmetics comprising the same Shiseido Co., Ltd. (JP) 2009-10-28 EP disclosed
US-20080081029-A1 acrylic homopolymers or copolymers, that can provide excellent hydrophobicity to powders or cosmetics, and can improve its rinsability SHISEIDO CO., LTD. (JP) 2008-04-03 US disclosed
EP-1803750-A1 SURFACE-TREATING AGENT, SURFACE-TREATED POWDER, AND COSMETIC PREPARATION CONTAINING SAME Shiseido Company, Limited (JP) 2007-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081029-A1 acrylic homopolymers or copolymers, that can provide excellent hydrophobicity to powders or cosmetics, and can improve its rinsability CHRM1, H1-0, H1-2 CA12 2086/4885CA7 2607/4885CA9 4152/4885
US-20110280946-A1 Surface-Treating Agents, Surface-Treated Powders, And Cosmetics Comprising The Same CHRM1, H1-0, H1-2 CA12 740/4885CA7 1422/4885CA9 3291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.