SCHEMBL1333090

SCHEMBL1333090

CCCC(C(=O)O)C(O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.50
CHRM1 P11229 1/20 0.50
AKR1A1 P14550 1/20 0.50
CHRM3 P20309 1/20 0.50
HTR2A P28223 1/20 0.50
HTR2C P28335 1/20 0.50
ADRA1A P35348 1/20 0.50
HRH1 P35367 1/20 0.50
DRD3 P35462 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
TSHR P16473 3/20 0.43
GPR84 Q9NQS5 3/20 0.41
FFAR1 O14842 1/20 0.41
GRIK1 P39086 1/20 0.39
SLC1A3 P43003 1/20 0.39
SLC1A2 P43004 1/20 0.39
SLC1A1 P43005 1/20 0.39
GRIK2 Q13002 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16794748 0.86 CA2 (0.50) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL6492260 0.86 CA2 (0.50) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL7186459 0.84 GPR84 (0.57) GPR84FFAR1GRIK1SLC1A2SLC1A1
SCHEMBL14110749 0.84 TDP1 (0.60) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL5031485 0.84 TDP1 (0.60) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL16794740 0.82 GPR84 (0.61) GPR84FFAR1GRIK1SLC1A2SLC1A1
SCHEMBL4282439 0.82 GPR84 (0.61) GPR84FFAR1GRIK1SLC1A2SLC1A1
SCHEMBL12920238 0.82 GPR84 (0.61) GPR84FFAR1GRIK1SLC1A2SLC1A1
SCHEMBL39649 0.82 TDP1 (0.52) TDP1CHRM1AKR1A1CHRM3HTR2A
SCHEMBL28212336 0.81 TDP1 (0.57) TDP1CHRM1AKR1A1CHRM3HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10340150-B2 Ni:NiGe:Ge selective etch formulations and method of using same ENTEGRIS, INC. (US) 2019-07-02 US claimed
US-20160314990-A1 NI:NIGE:GE SELECTIVE ETCH FORMULATIONS AND METHOD OF USING SAME ENTEGRIS, INC. (US) 2016-10-27 US claimed
US-20130225663-A1 LIPID DELIVERY FORMULATIONS DICERNA PHARMACEUTICALS, INC. (US) 2013-08-29 US claimed
WO-2011109294-A1 LIPID DELIVERY FORMULATIONS DICERNA PHARMACEUTICALS, INC. (US) 2011-09-09 WO claimed
CN-118624704-A Accurate control and ionization device for liquid drops for single-cell mass spectrometry and application of accurate control and ionization device 中国检验检疫科学研究院 2024-09-10 CN disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
EP-3080285-B1 PROCESSES TO PREPARE ELONGATED 2-KETOACIDS AND C6-C10 COMPOUNDS THEREFROM VIA GENETIC MODIFICATIONS TO MICROBIAL METABOLIC PATHWAYS DOW GLOBAL TECHNOLOGIES LLC (US) 2022-07-27 EP disclosed
US-10340150-B2 Ni:NiGe:Ge selective etch formulations and method of using same ENTEGRIS, INC. (US) 2019-07-02 US disclosed
US-9951356-B2 Processes to prepare elongated 2-ketoacids and C6-C10 compounds therefrom via genetic modifications to microbial metabolic pathways DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-24 US disclosed
US-9673030-B2 Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry EMORY UNIVERSITY (US) 2017-06-06 US disclosed
US-20160355850-A1 PROCESSES TO PREPARE ELONGATED 2-KETOACIDS AND C6-C10 COMPOUNDS THEREFROM VIA GENETIC MODIFICATIONS TO MICROBIAL METABOLIC PATHWAYS DOW AGROSCIENCES LLC 2016-12-08 US disclosed
US-20160314990-A1 NI:NIGE:GE SELECTIVE ETCH FORMULATIONS AND METHOD OF USING SAME ENTEGRIS, INC. (US) 2016-10-27 US disclosed
EP-3080285-A1 PROCESSES TO PREPARE ELONGATED 2-KETOACIDS AND C6-C10 COMPOUNDS THEREFROM VIA GENETIC MODIFICATIONS TO MICROBIAL METABOLIC PATHWAYS Dow Global Technologies LLC (US) 2016-10-19 EP disclosed
US-9320798-B2 Lipid delivery formulations DICERNA PHARMACEUTICALS, INC. (US) 2016-04-26 US disclosed
WO-2015089127-A1 PROCESSES TO PREPARE ELONGATED 2-KETOACIDS AND C6-C10 COMPOUNDS THEREFROM VIA GENETIC MODIFICATIONS TO MICROBIAL METABOLIC PATHWAYS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-06-18 WO disclosed
US-20130225663-A1 LIPID DELIVERY FORMULATIONS DICERNA PHARMACEUTICALS, INC. (US) 2013-08-29 US disclosed
US-20110282587-A1 COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY EMORY UNIVERSITY (US) 2011-11-17 US disclosed
WO-2011109294-A1 LIPID DELIVERY FORMULATIONS DICERNA PHARMACEUTICALS, INC. (US) 2011-09-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130225663-A1 LIPID DELIVERY FORMULATIONS LIPA, LIPC, CETP TDP1 4612/4885CHRM1 4796/4885AKR1A1 1846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.