Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 19/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394883 | 0.84 | TNIK (0.62) | TNIK | |
| SCHEMBL15713027 | 0.80 | TNIK (0.55) | TNIKTP53MAPT | |
| SCHEMBL15712779 | 0.78 | TNIK (0.51) | TNIKTP53MAPT | |
| SCHEMBL15667653 | 0.78 | TNIK (0.54) | TNIKMAPT | |
| SCHEMBL13333373 | 0.77 | KDM4E (0.47) | TNIKTP53MAPT | |
| SCHEMBL13333382 | 0.77 | TBK1 (0.45) | TNIKTP53MAPT | |
| SCHEMBL13333376 | 0.77 | TNIK (0.48) | TNIKTP53MAPT | |
| SCHEMBL13333406 | 0.77 | TNIK (0.50) | TNIKTP53MAPT | |
| SCHEMBL13333372 | 0.76 | TNIK (0.49) | TNIKTP53MAPT | |
| SCHEMBL13333153 | 0.75 | MAPT (0.51) | TNIKTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064111-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI (JP) | 2010-06-10 | — | — | WO | disclosed |