Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10045614 | 0.84 | L3MBTL1 (0.38) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL10045616 | 0.79 | LIMK1 (0.38) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL10045597 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL13335309 | 0.74 | GPR3 (0.41) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL13335313 | 0.72 | TNKS (0.35) | MEN1KMT2ARAB9AMAPTTNKS | |
| SCHEMBL13335314 | 0.69 | APP (0.43) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL13335315 | 0.66 | TNKS (0.36) | ALDH1A1KDM4EMEN1KMT2AHPGD | |
| SCHEMBL10045611 | 0.65 | TNKS (0.41) | ALDH1A1KDM4ERAB9AMAPTATM | |
| SCHEMBL15853288 | 0.63 | ATM (0.35) | MAPTATML3MBTL1 | |
| SCHEMBL17010959 | 0.63 | GPR3 (0.60) | ALDH1A1KDM4EMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100117066-A1 | Organic Semiconductors | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100117066-A1 | Organic Semiconductors | DBF4, DDT, SOAT1 | ALDH1A1 2333/4885KDM4E 297/4885MEN1 3151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.