Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319813 | 0.79 | PIM1 (0.36) | — | |
| SCHEMBL10045614 | 0.75 | L3MBTL1 (0.38) | — | |
| SCHEMBL13335319 | 0.75 | PGR (0.35) | HTR1DHTR1BPGR | |
| SCHEMBL16978722 | 0.71 | PGR (0.41) | HTR1DHTR1BPGR | |
| SCHEMBL2745245 | 0.67 | HTR1D (0.38) | HTR1DHTR1BPGR | |
| SCHEMBL18267858 | 0.67 | PGR (0.44) | HTR1DHTR1BPGR | |
| SCHEMBL18267867 | 0.67 | PGR (0.49) | HTR1DHTR1BPGR | |
| SCHEMBL12109800 | 0.66 | KCNH2 (0.39) | HTR1DHTR1BPGR | |
| SCHEMBL10013459 | 0.66 | CD38 (0.43) | — | |
| SCHEMBL18267829 | 0.65 | PGR (0.43) | HTR1DHTR1BPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100117066-A1 | Organic Semiconductors | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100117066-A1 | Organic Semiconductors | DBF4, DDT, SOAT1 | HTR1D 1187/4885HTR1B 1127/4885PGR 3013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.