Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | CCNC | P24863 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13335334 | 0.83 | HRH4 (0.31) | HRH4 | |
| SCHEMBL10045614 | 0.80 | L3MBTL1 (0.38) | PIM1PIM2HTT | |
| SCHEMBL13335339 | 0.79 | HTR1D (0.34) | — | |
| SCHEMBL17010965 | 0.70 | CYP2A6 (0.40) | PIM1PIM2HRH4PIM3CYP2A6 | |
| SCHEMBL9949673 | 0.70 | CYP2A6 (0.42) | PIM1PIM2HRH4PIM3CYP2A6 | |
| SCHEMBL3842558 | 0.69 | — | — | |
| SCHEMBL15853288 | 0.68 | ATM (0.35) | — | |
| SCHEMBL12278087 | 0.66 | GRM5 (0.31) | — | |
| SCHEMBL17426122 | 0.66 | GRM5 (0.31) | — | |
| SCHEMBL13335311 | 0.66 | ALDH1A1 (0.34) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100117066-A1 | Organic Semiconductors | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
| US-20100117066-A1 | Organic Semiconductors | MERCK PATENT GMBH (DE) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100117066-A1 | Organic Semiconductors | DBF4, DDT, SOAT1 | PIM1 1570/4885PIM2 1574/4885HRH4 1816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.