Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12634202 | 1.00 | CTNNB1 (0.32) | CTNNB1TCF7L2TRPA1P2RY14MCHR1 | |
| SCHEMBL15280006 | 0.96 | CXCR1 (0.33) | CTNNB1TCF7L2P2RY14MAPT | |
| SCHEMBL12573763 | 0.96 | CXCR1 (0.33) | CTNNB1TCF7L2P2RY14MAPT | |
| SCHEMBL29910200 | 0.94 | PLG (0.34) | P2RY14MCHR1 | |
| SCHEMBL12573714 | 0.94 | PLG (0.34) | P2RY14MCHR1 | |
| SCHEMBL1334049 | 0.94 | PLG (0.34) | P2RY14MCHR1 | |
| SCHEMBL1334089 | 0.93 | TRPA1 (0.34) | CTNNB1TCF7L2TRPA1P2RY14MCHR1 | |
| SCHEMBL12573766 | 0.90 | CXCR1 (0.33) | CTNNB1TCF7L2TRPA1P2RY14MAPT | |
| SCHEMBL2017036 | 0.90 | CXCR1 (0.33) | CTNNB1TCF7L2TRPA1P2RY14MAPT | |
| SCHEMBL12573790 | 0.90 | CXCR1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2652552-B9 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2016-02-17 | — | — | EP | claimed |
| EP-2652552-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2015-09-02 | — | — | EP | claimed |
| US-8545984-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | claimed |
| US-20110129678-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-02 | — | — | US | claimed |
| EP-2718755-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-05-29 | — | — | EP | disclosed |
| EP-2718754-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| EP-2895896-B1 | A PHOTOCHROMIC ARTICLE HAVING AT LEAST PARTIALLY CROSSED POLARIZED PHOTOCHROMIC-DICHROIC AND FIXED-POLARIZED LAYERS | TRANSITIONS OPTICAL INC (US) | 2022-11-02 | — | — | EP | disclosed |
| EP-2969499-B1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | TRANSITIONS OPTICAL INC (US) | 2021-12-08 | — | — | EP | disclosed |
| EP-2969468-B1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | TRANSITIONS OPTICAL INC (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-2652552-B9 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-2652552-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2015-09-02 | — | — | EP | disclosed |
| US-20140265010-A1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | TRANSITIONS OPTICAL LIMITED (IE) | 2014-09-18 | — | — | US | disclosed |
| US-20140264979-A1 | METHOD OF PREPARING PHOTOCHROMIC-DICHROIC FILMS HAVING REDUCED OPTICAL DISTORTION | TRANSITIONS OPTICAL LIMITED (IE) | 2014-09-18 | — | — | US | disclosed |
| US-8649081-B1 | Photochromic article having two at least partially crossed photochromic-dichroic layers | TRANSITIONS OPTICAL, INC. (US) | 2014-02-11 | — | — | US | disclosed |
| US-8582192-B2 | Polarizing photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-8545015-B2 | Polarizing photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8545984-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20110279883-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110129678-A1 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2011-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110129678-A1 | Photochromic compounds and compositions | CRY2, CRY1, PPOX | CTNNB1 734/4885TCF7L2 3932/4885TRPA1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.