Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | STAT1 | P42224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30914184 | 1.00 | ALOX5 (0.37) | ALOX5MAPTRAB9ASMN1; SMN2MAPK8 | |
| SCHEMBL29565401 | 0.96 | MAPK8 (0.37) | ALOX5MAPTRAB9ASMN1; SMN2MAPK8 | |
| SCHEMBL1333642 | 0.96 | MAPK8 (0.37) | ALOX5MAPTRAB9ASMN1; SMN2MAPK8 | |
| SCHEMBL5107968 | 0.90 | MAPK8 (0.41) | SMN1; SMN2MAPK8ALDH1A1KMT2AMEN1 | |
| SCHEMBL1332525 | 0.87 | ATM (0.40) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL29565863 | 0.87 | ATM (0.40) | MAPTRAB9ASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL5107921 | 0.87 | L3MBTL1 (0.40) | MAPTSMN1; SMN2MAPK8ALDH1A1KMT2A | |
| SCHEMBL6931279 | 0.85 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2MAPK8ALDH1A1KMT2A | |
| SCHEMBL13988961 | 0.83 | ALDH1A1 (0.35) | MAPTRAB9ASMN1; SMN2MAPK8ALDH1A1 | |
| SCHEMBL1332535 | 0.83 | KDM4E (0.35) | SMN1; SMN2MAPK8ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776436-B1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2019-05-08 | — | — | EP | claimed |
| US-7465415-B2 | Photochromic materials derived from ring-opening monomers and photochromic initiators | PPG INDUSTRIES OHIO, INC. (US) | 2008-12-16 | — | — | US | claimed |
| EP-1776436-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2007-04-25 | — | — | EP | claimed |
| WO-2006022825-A1 | PHOTOCHROMIC MATERIALS | TRANSITIONS OPTICAL, INC. (US) | 2006-03-02 | — | — | WO | claimed |
| US-20060022176-A1 | Reaction product of a ring-opening cyclic ester or carbonate and a photochromic initiator, especially a naphtho[1,2-b]quinone with one or more hydroxy groups, e.g., (1) 3,3-di(4-methoxyphenyl)-6,7-dimethoxy-13-methyl-13-(2-(2-hydroxyethoxy)ethoxy)-3H,13H-indeno[2,1-f]naphtho[1,2-b]pyran. | TRANSITIONS OPTICAL LIMITED (IE) | 2006-02-02 | — | — | US | claimed |
| EP-2718755-B1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL INC (US) | 2024-05-29 | — | — | EP | disclosed |
| US-8582192-B2 | Polarizing photochromic articles | TRANSITIONS OPTICAL, INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20110279883-A1 | POLARIZING PHOTOCHROMIC ARTICLES | TRANSITIONS OPTICAL, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-7465415-B2 | Photochromic materials derived from ring-opening monomers and photochromic initiators | PPG INDUSTRIES OHIO, INC. (US) | 2008-12-16 | — | — | US | disclosed |
| US-7465415-B2 | Photochromic materials derived from ring-opening monomers and photochromic initiators | PPG INDUSTRIES OHIO, INC. (US) | 2008-12-16 | — | — | US | disclosed |