Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159577 | 0.87 | PHLPP2 (0.32) | — | |
| SCHEMBL12053140 | 0.86 | KDM4E (0.36) | KDM4EMEN1NPC1MAPTHTT | |
| SCHEMBL13340930 | 0.84 | KDM4E (0.35) | KDM4EMEN1NPC1MAPTHTT | |
| SCHEMBL12052544 | 0.84 | THRB (0.37) | — | |
| SCHEMBL13793161 | 0.82 | ALDH1A1 (0.34) | KDM4EMEN1NPC1MAPTRAB9A | |
| SCHEMBL12052948 | 0.82 | PRMT1 (0.37) | KDM4EMEN1NPC1MAPTHTT | |
| SCHEMBL12053197 | 0.81 | KDM4E (0.38) | KDM4EMEN1NPC1MAPTHTT | |
| SCHEMBL12052525 | 0.81 | P2RX5 (0.32) | KDM4EMAPTRAB9ATDP1 | |
| SCHEMBL12052537 | 0.81 | PTGS1 (0.35) | MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL12052550 | 0.80 | THRB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8080101-B2 | Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-12-20 | — | — | US | disclosed |
| US-20080295732-A1 | Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use | DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE) | 2008-12-04 | — | — | US | disclosed |