SCHEMBL1334192

SCHEMBL1334192

Nc1ccc(-c2cccc3ccccc23)c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 4/20 0.62
ALDH1A1 P00352 4/20 0.62
CYP3A4 P08684 3/20 0.62
TSHR P16473 3/20 0.62
HSD17B10 Q99714 3/20 0.62
HPGD P15428 2/20 0.62
NFE2L2 Q16236 3/20 0.59
CRHBP P24387 1/20 0.59
CRHR2 Q13324 1/20 0.59
TDP1 Q9NUW8 3/20 0.52
HPRT1 P00492 1/20 0.47
IDO1 P14902 2/20 0.46
EP300 Q09472 2/20 0.46
KAT8 Q9H7Z6 2/20 0.46
HDAC3 O15379 1/20 0.46
KAT2B Q92831 1/20 0.46
NCOR2 Q9Y618 1/20 0.46
USP2 O75604 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30117590 1.00 KEAP1 (0.62) KEAP1ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL28450517 0.86 ALDH1A1 (0.57) KEAP1ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL866216 0.85 ALDH1A1 (0.61) KEAP1ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL6077039 0.85 ALDH1A1 (0.56) KEAP1ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL30851475 0.85 ALDH1A1 (0.61) KEAP1ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL56035 0.84 ALDH1A1 (0.65) KEAP1ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL29521589 0.84 ALDH1A1 (0.65) KEAP1ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL4943495 0.84 ALDH1A1 (0.52) KEAP1ALDH1A1CYP3A4TSHRHSD17B10
SCHEMBL30302654 0.84 KEAP1 (0.48) KEAP1ALDH1A1CYP3A4TSHRHSD17B10
Ammonia Solution, Strong SCHEMBL1656490 0.83 KEAP1 (0.58) KEAP1ALDH1A1CYP3A4TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115612403-B Self-assembled strong-adhesion copolymer film, coating method and application 中国科学院天津工业生物技术研究所 2023-12-01 CN claimed
WO-2023284777-A1 COPOLYMER FILM, ENZYME CATALYSIS SELF-ASSEMBLY SYNTHESIS METHOD THEREFOR, AND APPLICATION THEREOF 中国科学院天津工业生物技术研究所 2023-01-19 WO claimed
CN-115612403-A Self-assembly strong-adhesion copolymer film, film coating method and application 中国科学院天津工业生物技术研究所 2023-01-17 CN claimed
CN-115612114-A Copolymer membrane and enzymatic self-assembly synthesis method and application thereof 中国科学院天津工业生物技术研究所 2023-01-17 CN claimed
US-20250263421-A1 AMINE COMPOUND HAVING AZABENZOXAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME HODOGAYA CHEMICAL CO., LTD. (JP) 2025-08-21 US disclosed
EP-4357349-A1 AMINE COMPOUND HAVING AZABENZOXAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Hodogaya Chemical Co., Ltd. (JP) 2024-04-24 EP disclosed
CN-115612114-B Copolymer membrane and method for enzymatic self-assembly synthesis and application thereof 中国科学院天津工业生物技术研究所 2024-02-20 CN disclosed
CN-117279921-A Amine compound having azabenzoxazole ring structure and organic electroluminescent element using same 保土谷化学工业株式会社 2023-12-22 CN disclosed
CN-117203264-A Polyimide precursor composition and polyimide 杰富意化学株式会社 2023-12-08 CN disclosed
WO-2023195206-A1 POLYIMIDE PRECURSOR COMPOSITION AND POLYIMIDE JFEケミカル株式会社 2023-10-12 WO disclosed
EP-3521280-B1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-05-10 EP disclosed
US-20230012692-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-01-19 US disclosed
EP-1783147-A1 Composition and associated method GENERAL ELECTRIC COMPANY (US) 2007-05-09 EP disclosed
EP-1782881-A1 Membrane and associated method General Electric Company (US) 2007-05-09 EP disclosed
US-6949619-B2 Phenolic hydroxyl-bearing polyimide resin, making method and polyimide resin composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-09-27 US disclosed
US-20040019174-A1 Phenolic hydroxyl-bearing polyimide resin, making method and polyimide resin composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-01-29 US disclosed
US-5840369-A SCREEN PRINTING POLYIMIDE PRECURSOR INK ON SUBSTRATE, REMOVING SOLVENT, THERMALLY CURING INK TO FORM POLYIMIDE RELIEF PATTERN FILM CENTRAL GLASS CO., LTD. (JP) 1998-11-24 US disclosed
US-5686525-A THIXOTROPIC SCREEN PRINTING INK COMPRISING A HEAT TREATED POLYAMIC ACID SOLUTION OBTAINED BY REACTION OF AROMATIC TETRACARBOXYLIC ACID, DIAMINE AND A MALEIMIDE; RELIEF IMAGES CENTRAL GLASS COMPANY, LTD. (JP) 1997-11-11 US disclosed
US-5478918-A Low stress polyimide composition and precursor composition solution of same CENTRAL GLASS COMPANY, LIMITED (JP) 1995-12-26 US disclosed
EP-0659800-A1 Polyimide precursor composition, polyimide composition and process for the production of said polyimide composition CENTRAL GLASS COMPANY, LIMITED (JP) 1995-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263421-A1 AMINE COMPOUND HAVING AZABENZOXAZOLE RING STRUCTURE, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME AZI2, SLC39A7, EZH1 KEAP1 3159/4885ALDH1A1 261/4885CYP3A4 228/4885
US-20230012692-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME MAOA, SAT1, ALDH1A1 KEAP1 968/4885ALDH1A1 3/4885CYP3A4 1533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.