SCHEMBL866216

SCHEMBL866216

Nc1ccc(-c2ccc(N)c3ccccc23)c2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.61
CYP3A4 P08684 4/20 0.61
TDP1 Q9NUW8 3/20 0.61
HPGD P15428 3/20 0.61
TSHR P16473 2/20 0.61
HSD17B10 Q99714 2/20 0.61
KEAP1 Q14145 4/20 0.61
NFE2L2 Q16236 3/20 0.61
CRHBP P24387 1/20 0.61
CRHR2 Q13324 1/20 0.61
IDO1 P14902 2/20 0.59
EP300 Q09472 2/20 0.59
KAT8 Q9H7Z6 2/20 0.59
HDAC3 O15379 1/20 0.59
KAT2B Q92831 1/20 0.59
NCOR2 Q9Y618 1/20 0.59
CHEK1 O14757 1/20 0.52
NEK2 P51955 1/20 0.52
LIMK1 P53667 1/20 0.52
DYRK1A Q13627 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30851475 1.00 ALDH1A1 (0.61) ALDH1A1CYP3A4TDP1HPGDTSHR
Ammonia Solution, Strong SCHEMBL1656490 0.97 KEAP1 (0.58) ALDH1A1CYP3A4TDP1HPGDTSHR
SCHEMBL201893 0.90 ALDH1A1 (0.73) ALDH1A1CYP3A4TDP1HPGDTSHR
SCHEMBL29404342 0.90 ALDH1A1 (0.73) ALDH1A1CYP3A4TDP1HPGDTSHR
SCHEMBL24901300 0.87 ALDH1A1 (0.52) ALDH1A1CYP3A4TDP1HPGDTSHR
Hydrochloric Acid SCHEMBL7191297 0.87 CYP3A4 (0.69) ALDH1A1CYP3A4TDP1HPGDTSHR
SCHEMBL12320959 0.86 KEAP1 (0.54) ALDH1A1CYP3A4TDP1HPGDTSHR
SCHEMBL1334192 0.85 KEAP1 (0.62) ALDH1A1CYP3A4TDP1HPGDTSHR
SCHEMBL30117590 0.85 KEAP1 (0.62) ALDH1A1CYP3A4TDP1HPGDTSHR
SCHEMBL21854609 0.84 ALDH1A1 (0.87) ALDH1A1CYP3A4TDP1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210108032-A1 SOLVENT-FREE MELT POLYCONDENSATION PROCESS OF MAKING FURAN-BASED POLYAMIDES DUPONT IND BIOSCIENCES USA LLC (US) 2021-04-15 US claimed
US-20200283577-A1 SOLVENT-FREE MELT POLYCONDENSATION PROCESS OF MAKING FURAN-BASED POLYAMIDES DUPONT IND BIOSCIENCES USA LLC (US) 2020-09-10 US claimed
US-20180371167-A1 A SOLVENT-FREE MELT POLYCONDENSATION PROCESS OF MAKING FURAN-BASED POLYAMIDES DUPONT INDUSTRIAL BIOSCIENCES USA, LLC 2018-12-27 US claimed
EP-3390495-A1 A SOLVENT-FREE MELT POLYCONDENSATION PROCESS OF MAKING FURAN-BASED POLYAMIDES E. I. du Pont de Nemours and Company (US) 2018-10-24 EP claimed
EP-3383803-A1 FUEL CELL FOR WASTEWATER TREATMENT Imperial Innovations Ltd (GB) 2018-10-10 EP claimed
WO-2017106405-A1 A SOLVENT-FREE MELT POLYCONDENSATION PROCESS OF MAKING FURAN-BASED POLYAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2017-06-22 WO claimed
WO-2017093754-A1 FUEL CELL FOR WASTEWATER TREATMENT IMPERIAL INNOVATIONS LIMITED (GB) 2017-06-08 WO claimed
EP-1799791-B1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2016-01-13 EP claimed
WO-2013070026-A1 1,1'-BINAPHTHYL-4,4'-DIAMINE DERIVATIVES FOR LUMINESCENCE OF ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THEM SAMYANGEMS CO., LTD. (KR) 2013-05-16 WO claimed
US-7687118-B2 Photocrosslinkable materials ROLIC AG (CH) 2010-03-30 US claimed
US-20080069968-A1 Photocrosslinkable Materials ROLIC AG (CH) 2008-03-20 US claimed
EP-1799791-A1 PHOTOCROSSLINKABLE MATERIALS Rolic AG (CH) 2007-06-27 EP claimed
WO-2006039824-A1 PHOTOCROSSLINKABLE MATERIALS ROLIC AG (CH) 2006-04-20 WO claimed
WO-2026103790-A1 NAPHTHYRIDINE DERIVATIVE AND PREPARATION METHOD THEREFOR 江苏豪森药业集团有限公司 2026-05-21 WO disclosed
US-20250180952-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-06-05 US disclosed
EP-4493638-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2025-01-22 EP disclosed
US-5196164-A During addition polymerization, wall coating of anionic dye and cationic dye and organonitrogen compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 1993-03-23 US disclosed
EP-0017009-B1 DYES AND TINTS BASED ON OPTIONALLY SUBSTITUTED 2-AMINO-5-IMINOPYRROLENINES BAYER AG (DE) 1983-12-28 EP disclosed
EP-0017012-B1 DYES AND PROCESS FOR THE GENERATION OF TINTS BASED ON OPTIONALLY SUBSTITUTED 2-AMINO-5-IMINOPYRROLENINES BAYER AG (DE) 1983-10-05 EP disclosed
EP-0017009-A2 Dyes and tints based on optionally substituted 2-amino-5-iminopyrrolenines BAYER AG (DE) 1980-10-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080069968-A1 Photocrosslinkable Materials PARG, VSIR, IGLV6-57 ALDH1A1 1606/4885CYP3A4 4677/4885TDP1 2088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.